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. 1968 Sep;198(1):81–90. doi: 10.1113/jphysiol.1968.sp008594

A study of the end-plate potential in sodium-deficient solution

M Kordaš
PMCID: PMC1365310  PMID: 5677033

Abstract

1. The effect of anticholinesterases in lengthening the end-plate potential is much more pronounced in a low-sodium solution than in an ordinary Ringer-curare solution.

2. To investigate this difference, intracellular recordings of end-plate potentials and of end-plate currents in voltage-clamped muscle fibres were used.

3. It was found that the very large lengthening of the end-plate potential in a low-sodium solution was due to a combination of three factors: (i) lengthening of the underlying end-plate current, (ii) an increased membrane resistance and (iii) marked inward-going (anomalous) rectification of the muscle membrane.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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