Skip to main content
Biophysical Journal logoLink to Biophysical Journal
. 1963 Mar;3(2):155–166. doi: 10.1016/s0006-3495(63)86811-3

Incorporation of Ribonucleic Acid Bases into the Metabolic Pool and RNA of E. coli

M Buchwald, R J Britten
PMCID: PMC1366433  PMID: 14016541

Abstract

Labeled cytosine, adenine, and guanine are rapidly incorporated by E. coli. A fraction of the radioactivity passes directly into RNA with very little delay. The remainder enters a pool before being incorporated into RNA. The fractions entering the pool and the time constants for equilibration of the specific activity of the pool are widely different for the four RNA bases.

Full text

PDF
165

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. JACOB F., MONOD J. Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol. 1961 Jun;3:318–356. doi: 10.1016/s0022-2836(61)80072-7. [DOI] [PubMed] [Google Scholar]
  2. MIDGLEY J. E., McCARTHY B. J. The synthesis and kinetic behavior of deoxyribonucleic acid-like ribonucleic acid in bacteria. Biochim Biophys Acta. 1962 Nov 26;61:696–717. doi: 10.1016/0926-6550(62)90053-1. [DOI] [PubMed] [Google Scholar]

Articles from Biophysical Journal are provided here courtesy of The Biophysical Society

RESOURCES