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British Journal of Clinical Pharmacology logoLink to British Journal of Clinical Pharmacology
. 1991 Feb;31(2):193–196. doi: 10.1111/j.1365-2125.1991.tb05514.x

A dose-response study examining the effects of ritanserin on human slow wave sleep.

C Idzikowski 1, F J Mills 1, R J James 1
PMCID: PMC1368392  PMID: 1904750

Abstract

This study investigated the effects of placebo, 1 mg, 3 mg, 10 mg and 30 mg ritanserin and 10 mg diazepam on human sleep. Twelve normal volunteers participated in this randomized, double-blind, placebo-controlled cross-over sleep study. A clear dose-response relationship was found for ritanserin with higher doses evoking increased duration of slow wave sleep.

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Selected References

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