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. 2001 Jul;7(7):937–941. doi: 10.1017/s1355838201010299

Protein-RNA interactions in the subunits of human nuclear RNase P.

T Jiang 1, C Guerrier-Takada 1, S Altman 1
PMCID: PMC1370153  PMID: 11455963

Abstract

A yeast three-hybrid system was employed to analyze interactions in vivo between H1 RNA, the RNA subunit of human nuclear RNase P, and eight of the protein subunits of the enzyme. The genetic analysis indicates that subunits Rpp21, Rpp29, Rpp30, and Rpp38 interact directly with H1 RNA. The results of direct UV crosslinking studies of the purified RNase P holoenzyme confirm the results of the three-hybrid assay.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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