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. 1999 Jan;64(1):18–23. doi: 10.1086/302219

When less is more: gene loss as an engine of evolutionary change.

M V Olson 1
PMCID: PMC1377697  PMID: 9915938

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Selected References

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  1. Aggarwal A. K. Structure and function of restriction endonucleases. Curr Opin Struct Biol. 1995 Feb;5(1):11–19. doi: 10.1016/0959-440x(95)80004-k. [DOI] [PubMed] [Google Scholar]
  2. Ali M., Rellos P., Cox T. M. Hereditary fructose intolerance. J Med Genet. 1998 May;35(5):353–365. doi: 10.1136/jmg.35.5.353. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bickle T. A., Krüger D. H. Biology of DNA restriction. Microbiol Rev. 1993 Jun;57(2):434–450. doi: 10.1128/mr.57.2.434-450.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Board P., Coggan M., Johnston P., Ross V., Suzuki T., Webb G. Genetic heterogeneity of the human glutathione transferases: a complex of gene families. Pharmacol Ther. 1990;48(3):357–369. doi: 10.1016/0163-7258(90)90054-6. [DOI] [PubMed] [Google Scholar]
  5. Brody L. C., Biesecker B. B. Breast cancer susceptibility genes. BRCA1 and BRCA2. Medicine (Baltimore) 1998 May;77(3):208–226. doi: 10.1097/00005792-199805000-00006. [DOI] [PubMed] [Google Scholar]
  6. Bronson F. H., Heideman P. D. Lack of reproductive photoresponsiveness and correlative failure to respond to melatonin in a tropical rodent, the cane mouse. Biol Reprod. 1992 Feb;46(2):246–250. doi: 10.1095/biolreprod46.2.246. [DOI] [PubMed] [Google Scholar]
  7. Crawford D. H., Powell L. W., Leggett B. A., Francis J. S., Fletcher L. M., Webb S. I., Halliday J. W., Jazwinska E. C. Evidence that the ancestral haplotype in Australian hemochromatosis patients may be associated with a common mutation in the gene. Am J Hum Genet. 1995 Aug;57(2):362–367. [PMC free article] [PubMed] [Google Scholar]
  8. Gabriel S. E., Brigman K. N., Koller B. H., Boucher R. C., Stutts M. J. Cystic fibrosis heterozygote resistance to cholera toxin in the cystic fibrosis mouse model. Science. 1994 Oct 7;266(5182):107–109. doi: 10.1126/science.7524148. [DOI] [PubMed] [Google Scholar]
  9. Goebl M. G., Petes T. D. Most of the yeast genomic sequences are not essential for cell growth and division. Cell. 1986 Sep 26;46(7):983–992. doi: 10.1016/0092-8674(86)90697-5. [DOI] [PubMed] [Google Scholar]
  10. Goto M., Oshima I., Hasegawa M., Ebihara S. The locus controlling pineal serotonin N-acetyltransferase activity (Nat-2) is located on mouse chromosome 11. Brain Res Mol Brain Res. 1994 Feb;21(3-4):349–354. doi: 10.1016/0169-328x(94)90266-6. [DOI] [PubMed] [Google Scholar]
  11. Hall B. G., Xu L. Nucleotide sequence, function, activation, and evolution of the cryptic asc operon of Escherichia coli K12. Mol Biol Evol. 1992 Jul;9(4):688–706. doi: 10.1093/oxfordjournals.molbev.a040753. [DOI] [PubMed] [Google Scholar]
  12. Hall B. G., Yokoyama S., Calhoun D. H. Role of cryptic genes in microbial evolution. Mol Biol Evol. 1983 Dec;1(1):109–124. doi: 10.1093/oxfordjournals.molbev.a040300. [DOI] [PubMed] [Google Scholar]
  13. Harpending H. C., Batzer M. A., Gurven M., Jorde L. B., Rogers A. R., Sherry S. T. Genetic traces of ancient demography. Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1961–1967. doi: 10.1073/pnas.95.4.1961. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Jeltsch A., Kröger M., Pingoud A. Evidence for an evolutionary relationship among type-II restriction endonucleases. Gene. 1995 Jul 4;160(1):7–16. doi: 10.1016/0378-1119(95)00181-5. [DOI] [PubMed] [Google Scholar]
  15. Jeltsch A., Pingoud A. Horizontal gene transfer contributes to the wide distribution and evolution of type II restriction-modification systems. J Mol Evol. 1996 Feb;42(2):91–96. doi: 10.1007/BF02198833. [DOI] [PubMed] [Google Scholar]
  16. Karyagina A., Shilov I., Tashlitskii V., Khodoun M., Vasil'ev S., Lau P. C., Nikolskaya I. Specific binding of sso II DNA methyltransferase to its promoter region provides the regulation of sso II restriction-modification gene expression. Nucleic Acids Res. 1997 Jun 1;25(11):2114–2120. doi: 10.1093/nar/25.11.2114. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Libert F., Cochaux P., Beckman G., Samson M., Aksenova M., Cao A., Czeizel A., Claustres M., de la Rúa C., Ferrari M. The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe. Hum Mol Genet. 1998 Mar;7(3):399–406. doi: 10.1093/hmg/7.3.399. [DOI] [PubMed] [Google Scholar]
  18. NEEL J. V. Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? Am J Hum Genet. 1962 Dec;14:353–362. [PMC free article] [PubMed] [Google Scholar]
  19. Naito T., Kusano K., Kobayashi I. Selfish behavior of restriction-modification systems. Science. 1995 Feb 10;267(5199):897–899. doi: 10.1126/science.7846533. [DOI] [PubMed] [Google Scholar]
  20. O'hUigin C., Sato A., Klein J. Evidence for convergent evolution of A and B blood group antigens in primates. Hum Genet. 1997 Dec;101(2):141–148. doi: 10.1007/s004390050603. [DOI] [PubMed] [Google Scholar]
  21. Stephens J. C., Reich D. E., Goldstein D. B., Shin H. D., Smith M. W., Carrington M., Winkler C., Huttley G. A., Allikmets R., Schriml L. Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes. Am J Hum Genet. 1998 Jun;62(6):1507–1515. doi: 10.1086/301867. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Tamarkin L., Baird C. J., Almeida O. F. Melatonin: a coordinating signal for mammalian reproduction? Science. 1985 Feb 15;227(4688):714–720. doi: 10.1126/science.3881822. [DOI] [PubMed] [Google Scholar]
  23. Tournamille C., Colin Y., Cartron J. P., Le Van Kim C. Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals. Nat Genet. 1995 Jun;10(2):224–228. doi: 10.1038/ng0695-224. [DOI] [PubMed] [Google Scholar]
  24. Wilson G. G., Murray N. E. Restriction and modification systems. Annu Rev Genet. 1991;25:585–627. doi: 10.1146/annurev.ge.25.120191.003101. [DOI] [PubMed] [Google Scholar]

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