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British Journal of Clinical Pharmacology logoLink to British Journal of Clinical Pharmacology
. 1989 Sep;28(3):366–368. doi: 10.1111/j.1365-2125.1989.tb05440.x

Yohimbine increases human salivary secretion.

E Chatelut 1, Y Rispail 1, M Berlan 1, J L Montastruc 1
PMCID: PMC1379958  PMID: 2789932

Abstract

The effect of oral yohimbine (14 mg) on salivary secretion was evaluated in healthy volunteers. Yohimbine significantly increased salivary secretion when compared with placebo. This effect was significant from 60 min until 180 min after administration under our experimental conditions. Yohimbine (or alpha 2-adrenoceptor blocking agents) could have a potential interest in the treatment of dry mouths.

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Selected References

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