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. 1996 Feb;38(2):299–301. doi: 10.1136/gut.38.2.299

A case of Churg-Strauss syndrome: tissue diagnosis established by sigmoidoscopic rectal biopsy.

E J Leen 1, P J Rees 1, J D Sanderson 1, M L Wilkinson 1, M I Filipe 1
PMCID: PMC1383042  PMID: 8801216

Abstract

A case is presented of Churg-Strauss syndrome in a young man in whom the definitive diagnostic procedure was a full thickness sigmoidoscopic rectal biopsy, with submucosal sampling. Gastrointestinal changes in Churg-Strauss syndrome, a rare systemic illness characterised by asthma, blood and tissue eosinophilia, vasculitis, and granulomatous inflammation are common but poorly reported. The endoscopic and histopathological features of a case are described and emphasise the potential value of a limited sigmoidoscopy in establishing the diagnosis, when lower gastrointestinal symptoms are present.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Lanham J. G., Elkon K. B., Pusey C. D., Hughes G. R. Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg-Strauss syndrome. Medicine (Baltimore) 1984 Mar;63(2):65–81. doi: 10.1097/00005792-198403000-00001. [DOI] [PubMed] [Google Scholar]
  2. Modigliani R., Muschart J. M., Galian A., Clauvel J. P., Piel-Desruisseaux J. L. Allergic granulomatous vasculitis (Churg-Strauss Syndrome). Report of a case with widespread digestive involvement. Dig Dis Sci. 1981 Mar;26(3):264–270. doi: 10.1007/BF01391641. [DOI] [PubMed] [Google Scholar]
  3. Naylor A. R., Pollet J. E. Eosinophilic colitis. Dis Colon Rectum. 1985 Aug;28(8):615–618. doi: 10.1007/BF02554161. [DOI] [PubMed] [Google Scholar]
  4. Partyka E. K., Sanowski R. A., Kozarek R. A. Colonoscopic features of eosinophilic gastroenteritis. Dis Colon Rectum. 1980 Jul-Aug;23(5):353–356. doi: 10.1007/BF02586845. [DOI] [PubMed] [Google Scholar]
  5. Parums D. V. The arteritides. Histopathology. 1994 Jul;25(1):1–20. doi: 10.1111/j.1365-2559.1994.tb00593.x. [DOI] [PubMed] [Google Scholar]
  6. Schoretsanitis G. N., Wakely D. M., Maddox T., Wastell C. A case of Churg-Strauss vasculitis complicated by small bowel necrosis. Postgrad Med J. 1993 Oct;69(816):828–831. doi: 10.1136/pgmj.69.816.828. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Shimamoto C., Hirata I., Ohshiba S., Fujiwara S., Nishio M. Churg-Strauss syndrome (allergic granulomatous angiitis) with peculiar multiple colonic ulcers. Am J Gastroenterol. 1990 Mar;85(3):316–319. [PubMed] [Google Scholar]
  8. Tedesco F. J., Huckaby C. B., Hamby-Allen M., Ewing G. C. Eosinophilic ileocolitis: expanding spectrum of eosinophilic gastroenteritis. Dig Dis Sci. 1981 Oct;26(10):943–948. doi: 10.1007/BF01309502. [DOI] [PubMed] [Google Scholar]

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