Skip to main content
Annals of Surgery logoLink to Annals of Surgery
. 1969 Oct;170(4):617–632. doi: 10.1097/00000658-196910000-00013

Anti-serum to cultured human lymphoblasts: preparation, purification and immunosuppressive properties in man.

J S Najarian, R L Simmons, H Gewurz, A Moberg, F Merkel, G E Moore
PMCID: PMC1387783  PMID: 4186508

Full text

PDF
629

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Golub E. S., Weigle W. O. Studies on the induction of immunologic unresponsiveness. 3. Antigen form and mouse strain variation. J Immunol. 1969 Feb;102(2):389–396. [PubMed] [Google Scholar]
  2. Halpern B., Cachera J. P., Lacombe M., Hathaway A., Crepin Y., Hung B. M., Lacassagne J. P., Leandri J., Laurent D., Dubost C. The efficiency of sheep antidog antilymphocyte serum (SADALS) in the prolongation of canine heart allografts. Transplant Proc. 1969 Mar;1(1):467–469. [PubMed] [Google Scholar]
  3. Howard R. J., Dougherty S. F., Mergenhagen S. E. Prolongation of skin homografts by rabbit anti-mouse lymphocyte serum in mice rendered tolerant to rabbit gamma-globulin. J Immunol. 1968 Aug;101(2):301–307. [PubMed] [Google Scholar]
  4. Immons R. L., Ozerkis A. J., Hoehn R. J. Antiserum to lymphocytes: interactions with chemical immunosuppressants. Science. 1968 Jun 7;160(3832):1127–1130. doi: 10.1126/science.160.3832.1127. [DOI] [PubMed] [Google Scholar]
  5. Iwasaki Y., Porter K. A., Amend J. R., Marchioro T. L., Zühlke V., Starzl T. E. The preparation and testing of horse antidog and antihuman antilymphoid plasma or serum and its protein fractions. Surg Gynecol Obstet. 1967 Jan;124(1):1–24. [PMC free article] [PubMed] [Google Scholar]
  6. JEEJEEBHOY H. F. EFFECTS OF RABBIT ANTI-RAT-LYMPHOCYTE PLASMA ON IMMUNE RESPONSE OF RATS THYMECTOMISED IN ADULT LIFE. Lancet. 1965 Jul 17;2(7403):106–107. doi: 10.1016/s0140-6736(65)92222-1. [DOI] [PubMed] [Google Scholar]
  7. Levey R. H., Medawar P. B. Nature and mode of action of antilymphocytic antiserum. Proc Natl Acad Sci U S A. 1966 Oct;56(4):1130–1137. doi: 10.1073/pnas.56.4.1130. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Mitchell R. M., Sheil A. G., Slafsky S. F., Murray J. E. The effect of heterologous immune serum on canine renal homografts. Transplantation. 1966 May;4(3):323–329. doi: 10.1097/00007890-196605000-00009. [DOI] [PubMed] [Google Scholar]
  9. Monaco A. P., Abbott W. M., Othersen H. B., Simmons R. L., Wood M. L., Flax M. H., Russell P. S. Antiserum to lymphocytes: prolonged survival of canine renal allografts. Science. 1966 Sep 9;153(3741):1264–1267. doi: 10.1126/science.153.3741.1264. [DOI] [PubMed] [Google Scholar]
  10. Monaco A. P., Wood M. L., Russell P. S. Adult Thymectomy: Effect on Recovery from Immunologic Depression in Mice. Science. 1965 Jul 23;149(3682):432–435. doi: 10.1126/science.149.3682.432. [DOI] [PubMed] [Google Scholar]
  11. Monaco A. P., Wood M. L., Russell P. S. Some effects of purified heterologous antihuman lymphocyte serum in man. Transplantation. 1967 Jul;5(4 Suppl):1106–1114. doi: 10.1097/00007890-196707001-00046. [DOI] [PubMed] [Google Scholar]
  12. Nagaya H., Sieker H. O. Allograft survival: effect of antiserums to thymus glands and lymphocytes. Science. 1965 Nov 26;150(3700):1181–1182. doi: 10.1126/science.150.3700.1181. [DOI] [PubMed] [Google Scholar]
  13. Perper R. J., Okimoto J. T., Cochrum K. C., Ramsey N., Najarian J. S. A rapid method for purification of large quantities of anti-lymphocytic serum. Proc Soc Exp Biol Med. 1967 Jun;125(2):575–580. doi: 10.3181/00379727-125-32150. [DOI] [PubMed] [Google Scholar]
  14. Pichlmayr R., Brendel W., Zenker R. Production and effect of heterologous anti-canine lymphocyte serum. Surgery. 1967 May;61(5):774–783. [PubMed] [Google Scholar]
  15. Starzl T. E., Brettschneider L., Penn I., Schmidt R. W., Bell P., Kashiwagi N., Townsend C. M., Putnam C. W. A trial with heterologous antilymphocyte globulin in man. Transplant Proc. 1969 Mar;1(1):448–454. [PMC free article] [PubMed] [Google Scholar]
  16. Starzl T. E., Marchioro T. L., Porter K. A., Iwasaki Y., Cerilli G. J. The use of heterologous antilymphoid agents in canine renal and liver homotransplantation and in human renal homotransplantation. Surg Gynecol Obstet. 1967 Feb;124(2):301–308. [PMC free article] [PubMed] [Google Scholar]
  17. Terasaki P. I., Vredevoe D. L., Mickey M. R. Serotyping for homotransplantation. X. Survival of 196 grafted kidneys subsequent to typing. Transplantation. 1967 Jul;5(4 Suppl):1057–1070. doi: 10.1097/00007890-196707001-00041. [DOI] [PubMed] [Google Scholar]
  18. WAKSMAN B. H., ARBOUYS S., ARNASON B. G. The use of specific "lymphocyte" antisera to inhibit hypersensitive reactions of the "delayed" type. J Exp Med. 1961 Dec 1;114:997–1022. doi: 10.1084/jem.114.6.997. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. WOODRUFF M. F., ANDERSON N. F. THE EFFECT OF LYMPHOCYTE DEPLETION BY THORACIC DUCT FISTULA AND ADMINISTRATION OF ANTILYMPHOCYTIC SERUM ON THE SURVIVAL OF SKIN HOMOGRAFTS IN RATS. Ann N Y Acad Sci. 1964 Nov 30;120:119–128. doi: 10.1111/j.1749-6632.1964.tb34710.x. [DOI] [PubMed] [Google Scholar]
  20. Weil R., 3rd, Simmons R. L. Combined immunosuppression for canine renal allograft prolongation: antilymphocyte serum plus prednisolone or azathioprine. Ann Surg. 1968 Feb;167(2):239–245. doi: 10.1097/00000658-196802000-00013. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Annals of Surgery are provided here courtesy of Lippincott, Williams, and Wilkins

RESOURCES