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. 1978 Nov;188(5):611–622. doi: 10.1097/00000658-197811000-00005

The preclotting of porous arterial prostheses.

S G Yates, A A Barros D'Sa, K Berger, L G Fernandez, S J Wood, E A Rittenhouse, C C Davis, P B Mansfield, L R Sauvage
PMCID: PMC1396781  PMID: 152614

Abstract

A four-step preclotting method is presented for use with porous filamentous Dacron prostheses in the fully-heparinized patient. The method employs controlled fibrin formation within graft interstices, heparin neutralization of all thrombin remaining in the graft wall, and delay of systemic heparin neutralization until 15--20 minutes after clamp release. The resulting flow surface is impervious, smooth and hypothrombogenic. Experimental data are presented which support the rationale of this four-step preclotting method. Four years of clinical experience with the method are summarized, involving 300 prosthesis limbs used in aortic bifurcation, aortofemoral, femorofemoral, axillary-femoral and femoropopliteal positions in 192 patients. A clinical perspective of preclotting techniques is presented in which the proper use of this new method is suggested.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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