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. 1981 Jan;11(1):85–88. doi: 10.1111/j.1365-2125.1981.tb01107.x

Radioimmunoassay for perphenazine in human plasma.

K K Midha, C Mackonka, J K Cooper, J W Hubbard, P K Yeung
PMCID: PMC1401697  PMID: 7213513

Abstract

1 A new sensitive, specific and rapid radioimmunoassay procedure for the determination of plasma concentrations of the neuroleptic drug perphenazine is described. 2 The antiserum developed for perphenazine did not cross-react with most of the major metabolites of perphenazine nor the tricyclic antidepressants and antianxiety agents commonly co-administered with the drug. 3 The assay, based on the above antiserum, enabled the quantitation of 50 pg of the drug in 200 microliters of plasma with a coefficient of variation of about 8% and therefore should be applicable for single dose pharmacokinetic studies, as well as therapeutic monitoring of the drug in patients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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