Skip to main content
British Journal of Clinical Pharmacology logoLink to British Journal of Clinical Pharmacology
letter
. 1981 Oct;12(4):591–592. doi: 10.1111/j.1365-2125.1981.tb01273.x

Serum protein binding of diazepam and its displacement by valproic acid in vitro.

S Dhillon, A Richens
PMCID: PMC1401889  PMID: 6794588

Full text

PDF
591

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Colburn W. A., Gibaldi M. Plasma protein binding of diazepam after a single dose of sodium oleate. J Pharm Sci. 1978 Jun;67(6):891–892. doi: 10.1002/jps.2600670652. [DOI] [PubMed] [Google Scholar]
  2. Klotz U., Antonin K. H., Bieck P. R. Pharmacokinetics and plasma binding of diazepam in man, dog, rabbit, guinea pig and rat. J Pharmacol Exp Ther. 1976 Oct;199(1):67–73. [PubMed] [Google Scholar]
  3. Kober A., Sjöholm I., Borgå O., Odar-Cederlöf I. Protein binding of diazepam and digitoxin in uremic and normal serum. Biochem Pharmacol. 1979 Apr 1;28(7):1037–1042. doi: 10.1016/0006-2952(79)90300-9. [DOI] [PubMed] [Google Scholar]
  4. Lunde P. K., Rane A., Yaffe S. J., Lund L., Sjöqvist F. Plasma protein binding of diphenylhydantoin in man. Interaction with other drugs and the effect of temperature and plasma dilution. Clin Pharmacol Ther. 1970 Nov-Dec;11(6):846–855. doi: 10.1002/cpt1970116846. [DOI] [PubMed] [Google Scholar]
  5. Monks A., Richens A. Serum protein binding of valproic acid and its displacement by palmitic acid in vitro. Br J Clin Pharmacol. 1979 Aug;8(2):187–189. doi: 10.1111/j.1365-2125.1979.tb05820.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Müller W., Wollert U. Characterization of the binding of benzodiazepines to human serum albumin. Naunyn Schmiedebergs Arch Pharmacol. 1973;280(3):229–237. doi: 10.1007/BF00501348. [DOI] [PubMed] [Google Scholar]
  7. Sjödin T. Circular dichroism studies on the inhibiting effect of oleic acid on the binding of diazepam to human serum albumin. Biochem Pharmacol. 1977 Nov 15;26(22):2157–2161. doi: 10.1016/0006-2952(77)90268-4. [DOI] [PubMed] [Google Scholar]
  8. Symposium on drug protein binding. Biochemical, pharmacokinetic and clinical implications. Stockholm, March 26--28, 1980. Abstracts. Acta Pharm Suec. 1980;17(2):65–104. [PubMed] [Google Scholar]
  9. Thiessen J. J., Sellers E. M., Denbeigh P., Dolman L. Plasma protein binding of diazepam and tolbutamide in chronic alcoholics. J Clin Pharmacol. 1976 Jul;16(7):345–351. doi: 10.1002/j.1552-4604.1976.tb01531.x. [DOI] [PubMed] [Google Scholar]
  10. Tsutsumi E., Inaba T., Mahon W. A. The displacing effect of a fatty acid on the binding of diazepam to human serum albumin. Biochem Pharmacol. 1975 Jul 15;24(13-14):1361–1362. doi: 10.1016/0006-2952(75)90355-x. [DOI] [PubMed] [Google Scholar]
  11. van der Klejin E., van Rossum J. M., Muskens E. T., Rijntjes N. V. Pharmacokinetics of diazepam in dogs, mice and humans. Acta Pharmacol Toxicol (Copenh) 1971;29 (Suppl 3):109–127. doi: 10.1111/j.1600-0773.1971.tb03291.x. [DOI] [PubMed] [Google Scholar]

Articles from British Journal of Clinical Pharmacology are provided here courtesy of British Pharmacological Society

RESOURCES