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. 1990 May;80(5):590–593. doi: 10.2105/ajph.80.5.590

Persistence of anti-HBs among health care personnel immunized with hepatitis B vaccine.

M T Pasko 1, T R Beam Jr 1
PMCID: PMC1404632  PMID: 2139306

Abstract

Health care personnel who received the hepatitis B vaccine (Heptavax-BR, MSD) were followed for persistence of hepatitis B surface antibody (anti-HBs). Response occurred in 135/146 (92.5 percent) vaccinees. Loss of anti-HBs (less than 72 RIA units; 10 S/N) occurred in 35.9 percent during the 36-month surveillance. Stepwise discriminant analysis found age and magnitude of initial antibody level, but not weight-height index, to be predictive of antibody loss over the 36 months. Twenty-four of 27 employees (88.9 percent) who lost anti-HBs responded to a fourth vaccine dose. In contrast, three of eight initial non-responders (37.5 percent) developed antibody after a fourth vaccine dose.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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