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. 1968 Mar;14(3):409–414.

Further studies of antigen stimulation of deoxyribonucleic acid synthesis in rabbit spleen cell cultures

I. The effects of centrifuged proteins

G Harris, W A Cramp
PMCID: PMC1409330  PMID: 4170511

Abstract

The rate of DNA synthesis, as measured by the uptake of [14C]thymidine by spleen cell suspensions from rabbits previously immunized to heterologous proteins, was specifically stimulated by the deposits obtained after high-speed centrifugation of solutions of these antigens.

The deposited material was much more stimulatory than the original protein or the supernatants from centrifuged preparations. Recombination of the centrifuged deposit with the supernatant resulted in restoration of the lost stimulatory activity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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