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. 1968 Mar;14(3):319–324.

Vibriocidal activity, immune globulin producing cells and immune globulin levels in Theropithecus gelada after administration of a Vibrio cholerae antigen

Oscar Felsenfeld, William E Greer
PMCID: PMC1409338  PMID: 4170509

Abstract

Geladas were fed or injected with an antigen that contained Burrows' type 2 cholera toxin. Rising agglutinin and vibriocidal titres were observed in the serum, peripheral and mesenteric lymph nodes, spleen and lymphatic tissue of the upper intestine. Oral administration stimulated a more intensive vibriocidal activity in the mesenteric lymphatic nodes and intestinal lymphatic tissue, and within a shorter time than parenteral injection of the same antigen. Immune globulin synthesis paralleled largely the number of immunologically active cells. The agglutinin titres reflected the level of immune globulins and the numbers of globulin producing cells, whereas vibriocidal titres appeared independent of both. In terms of antibody site serum IgG was weight for weight more vibriocidal than serum IgM.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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