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. 1968 Nov;15(5):671–679.

The cellular transfer of immunity to Trichostrongylus colubriformis in an isogenic strain of guinea-pig

IV. The localization of immune lymphocytes in small intestine in infected and non-infected guinea-pigs

J K Dineen, P M Ronai, B M Wagland
PMCID: PMC1409527  PMID: 5697015

Abstract

Immune and non-immune mesenteric lymph node and Peyer's patch cells were labelled in vitro with 51Cr and injected intravenously into infected and non-infected syngeneic guinea-pigs (Heston strain). From the distribution of the radioactive label in the small intestine (the site of infection of T. colubriformis) it was concluded that immune lymphocytes: (1) preferentially localize or `home in' on the infection, (2) come into intimate contact with the parasite in the epithelium, and (3) rapidly undergo `allergic death' or lysis at the site of infection.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Dineen J. K., Wagland B. M., Ronai P. M. The cellular transfer of immunity to Trichostrongylus colubriformis in an isogenic strain of guinea-pig. 3. The localization and functional activity of immune lymph node cells following syngeneic and allogeneic transfer. Immunology. 1968 Sep;15(3):335–341. [PMC free article] [PubMed] [Google Scholar]
  2. Dineen J. K., Wagland B. M. The cellular transfer of immunity to Trichostrongylus colubriformis in an isogenic strain of guinea-pig. II. The relative susceptibility of the larval and adult stages of the parasite to immunological attack. Immunology. 1966 Jul;11(1):47–57. [PMC free article] [PubMed] [Google Scholar]
  3. Hall J. G. Studies of the cells in the afferent and efferent lymph of lymph nodes draining the site of skin homografts. J Exp Med. 1967 May 1;125(5):737–754. doi: 10.1084/jem.125.5.737. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. MITCHISON N. A. Studies on the immunological response to foreign tumor transplants in the mouse. I. The role of lymph node cells in conferring immunity by adoptive transfer. J Exp Med. 1955 Aug 1;102(2):157–177. doi: 10.1084/jem.102.2.157. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. McCALL M. S., SUTHERLAND D. A., EISENTRAUT A. M., LANZ H. The tagging of leukemic leukocytes with radioactive chromium and measurement of the in vivo cell survival. J Lab Clin Med. 1955 May;45(5):717–724. [PubMed] [Google Scholar]
  6. PRENDERGAST R. A. CELLULAR SPECIFICITY IN THE HOMOGRAFT REACTION. J Exp Med. 1964 Mar 1;119:377–388. doi: 10.1084/jem.119.3.377. [DOI] [PMC free article] [PubMed] [Google Scholar]

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