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. 1970 Feb;11(2):141–148. doi: 10.1136/gut.11.2.141

Cholelithiasis in Singapore

Part I A necropsy study

W S Hwang
PMCID: PMC1411354  PMID: 5441883

Abstract

The present necropsy study shows an oriental pattern of gallstone disease in Singapore, namely, a relatively low overall frequency, an equal involvement of both sexes, a high proportion of pigment stones, and the common occurrence of choledocholithiasis associated with pyogenic cholangitis.

There is a close association between opium addiction and cholelithiasis in the adult male Chinese in Singapore, and the long-term abuse of opium may be an important aetiological factor in the pathogenesis of oriental cholelithiasis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CLELAND J. B. Gall-stones in seven thousand post-mortem examinations. Med J Aust. 1953 Sep 26;2(13):488–489. [PubMed] [Google Scholar]
  2. COBO A., HALL R. C., TORRES E., CUELLO C. J. INTRAHEPATIC CALCULI. Arch Surg. 1964 Dec;89:936–941. doi: 10.1001/archsurg.1964.01320060004002. [DOI] [PubMed] [Google Scholar]
  3. COOK J., HOU P. C., HO H. C., McFADZEAN A. J. Recurrent pyogenic cholangeitis. Br J Surg. 1954 Sep;42(172):188–203. doi: 10.1002/bjs.18004217211. [DOI] [PubMed] [Google Scholar]
  4. Chou S. T., Gibson J. B. Experimental cholangitis and cholelithiasis. Br J Exp Pathol. 1968 Dec;49(6):565–573. [PMC free article] [PubMed] [Google Scholar]
  5. DINEEN P. THE IMPORTANCE OF THE ROUTE OF INFECTION IN EXPERIMENTAL BILIARY TRACT OBSTRUCTION. Surg Gynecol Obstet. 1964 Nov;119:1001–1008. [PubMed] [Google Scholar]
  6. Flemma R. J., Flint L. M., Osterhout S., Shingleton W. W. Bacteriologic studies of biliary tract infection. Ann Surg. 1967 Oct;166(4):563–572. doi: 10.1097/00000658-196710000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. HARRISON-LEVY A. The biliary obstruction syndrome of the Chinese. Br J Surg. 1962 May;49:674–685. doi: 10.1002/bjs.18004921824. [DOI] [PubMed] [Google Scholar]
  8. Hur K. B., Rice R. G., Hong S. S. Cholelithiasis in Koreans. Yonsei Med J. 1963;4:103–118. doi: 10.3349/ymj.1963.4.1.103. [DOI] [PubMed] [Google Scholar]
  9. KOZOLL D. D., DWYER G., MEYER K. A. Pathologic correlation of gallstones: a review of 1,847 autopsies of patients with gallstones. Arch Surg. 1959 Sep;79:514–536. doi: 10.1001/archsurg.1959.04320090162026. [DOI] [PubMed] [Google Scholar]
  10. LIEBER M. M. The incidence of gallstones and their correlation with other diseases. Ann Surg. 1952 Mar;135(3):394–405. doi: 10.1097/00000658-195203000-00011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. MAKI T. Cholelithiasis in the Japanese. Arch Surg. 1961 Apr;82:599–612. doi: 10.1001/archsurg.1961.01300100113013. [DOI] [PubMed] [Google Scholar]
  12. MUIR C. S. DEMOGRAPHY AND AGE-SEX DISTRIBUTION OF THE AUTOPSY POPULATIONS OF MULTIRACIAL SINGAPORE. Singapore Med J. 1964 Sep;4:96–104. [PubMed] [Google Scholar]
  13. NEWMAN H. F., NORTHUP J. D. The autopsy incidence of gallstones. Surg Gynecol Obstet. 1959 Jul;109(1):1–13. [PubMed] [Google Scholar]
  14. ONG G. B. A study of recurrent pyogenic cholangitis. Arch Surg. 1962 Feb;84:199–225. doi: 10.1001/archsurg.1962.01300200047004. [DOI] [PubMed] [Google Scholar]
  15. STITNIMANKARN T. The necropsy incidence of gallstones in Thailand. Am J Med Sci. 1960 Sep;240:349–352. doi: 10.1097/00000441-196009000-00012. [DOI] [PubMed] [Google Scholar]
  16. STOCK F. E., FUNG J. H. Oriental cholangiohepatitis. Arch Surg. 1962 Apr;84:409–412. doi: 10.1001/archsurg.1962.01300220033004. [DOI] [PubMed] [Google Scholar]
  17. TEOH T. B. A study of gall-stones and included worms in recurrent pyogenic cholangitis. J Pathol Bacteriol. 1963 Jul;86:123–129. doi: 10.1002/path.1700860115. [DOI] [PubMed] [Google Scholar]
  18. TORVIK A., HOIVIK B. Gallstones in an autopsy series. Incidence, complications, and correlations with carcinoma of the gallbladder. Acta Chir Scand. 1960 Nov 25;120:168–174. [PubMed] [Google Scholar]

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