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. 1977 Apr;18(4):295–300. doi: 10.1136/gut.18.4.295

Symptomatic significance of gastric mucosal changes after surgery for peptic ulcer.

A M Hoare, E L Jones, J Alexander-Williams, C F Hawkins
PMCID: PMC1411451  PMID: 863289

Abstract

Eighty-four patients who had undergone different types of operation for duodenal ulcer have been studied by endoscopy and gastric biopsy. Half suffered from dyspepsia and vomiting but the other half had no symptoms and acted as controls. Endoscopic and histological abnormalities were found in both groups of patients. However, certain findings occurred more commonly in those with symptoms; severe and extensive hyperaemia, bile staining of the gastric mucus, and bile reflux seen on endoscopy were all significantly more common in those with symptoms than in those without. Active gastritis in the proximal stomach was also more common in those with symptoms. Gastritis of the stoma and antrum was found in 89% of all patients; as it was unconnected with symptoms it can be regarded as a "normal" finding. The incidences of contact bleeding, erosions, and oedema were not significantly different in the two groups.

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Selected References

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  1. Aukee S., Krohn K. Occurrence and progression of gastritis in patients operated on for peptic ulcer. Scand J Gastroenterol. 1972;7(6):541–546. doi: 10.3109/00365527209180953. [DOI] [PubMed] [Google Scholar]
  2. BENEDICT E. B. A gastroscopic biopsy study of 50 postoperative stomachs. Gastroenterology. 1960 Feb;38:267–268. [PubMed] [Google Scholar]
  3. Black R. B., Roberts G., Rhodes J. The effect of healing on bile reflux in gastric ulcer. Gut. 1971 Jul;12(7):552–558. doi: 10.1136/gut.12.7.552. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Capper W. M., Airth G. R., Kilby J. O. A test for pyloric regurgitation. Lancet. 1966 Sep 17;2(7464):621–623. doi: 10.1016/s0140-6736(66)91930-1. [DOI] [PubMed] [Google Scholar]
  5. Cotton P. B., Rosenberg M. T., Axon A. T., Davis M., Pierce J. W., Price A. B., Stevenson G. W., Waldram R. Diagnostic yield of fibre-optic endoscopy in the operated stomach. Br J Surg. 1973 Aug;60(8):629–632. doi: 10.1002/bjs.1800600813. [DOI] [PubMed] [Google Scholar]
  6. Herrington J. L., Jr, Sawyers J. L., Whitehead W. A. Surgical management of reflux gastritis. Ann Surg. 1974 Oct;180(4):526–537. doi: 10.1097/00000658-197410000-00017. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hirschowitz B. I., Luketic G. C. Endoscopy in the post-gastrectomy patient. An analysis of 580 patients. Gastrointest Endosc. 1971 Aug;18(1):27–30. doi: 10.1016/s0016-5107(71)74015-2. [DOI] [PubMed] [Google Scholar]
  8. Johnston D. H. A biopsy study of the gastric mucosa in postoperative patients with and without marginal ulcer. Am J Gastroenterol. 1966 Aug;46(2):103–118. [PubMed] [Google Scholar]
  9. Joseph W. L., Rivera R. A., O'Kieffe D. A., Geelhoed G. W., McCune W. S. Management of postoperative alkaline reflux gastritis. Ann Surg. 1973 Jun;177(6):655–659. doi: 10.1097/00000658-197306000-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Keighley M. R., Asquith P., Alexander-Williams J. Duodenogastric reflux: a cause of gastric mucosal hyperaemia and symptoms after operations for peptic ulceration. Gut. 1975 Jan;16(1):28–32. doi: 10.1136/gut.16.1.28. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. LAWSON H. H. EFFECT OF DUODENAL CONTENTS ON THE GASTRIC MUCOSA UNDER EXPERIMENTAL CONDITIONS. Lancet. 1964 Feb 29;1(7331):469–472. doi: 10.1016/s0140-6736(64)90800-1. [DOI] [PubMed] [Google Scholar]
  12. LEES F., GRANDJEAN L. C. The gastric and jejunal mucosae in healthy patients with partial gastrectomy. AMA Arch Intern Med. 1958 May;101(5):943–951. doi: 10.1001/archinte.1958.00260170099013. [DOI] [PubMed] [Google Scholar]
  13. Lawson H. H. The reversibility of postgastrectomy alkaline reflux gastritis by a Roux-en-Y loop. Br J Surg. 1972 Jan;59(1):13–15. doi: 10.1002/bjs.1800590104. [DOI] [PubMed] [Google Scholar]
  14. O'Neill M., Whelton M. J., Doyle C., Shorten E., Hennessy T. Endoscopic findings in patients after definitive gastric surgery. Ir Med J. 1975 Jan 11;68(1):9–12. [PubMed] [Google Scholar]
  15. Rhodes J., Barnardo D. E., Phillips S. F., Rovelstad R. A., Hofmann A. F. Increased reflux of bile into the stomach in patients with gastric ulcer. Gastroenterology. 1969 Sep;57(3):241–252. [PubMed] [Google Scholar]
  16. Simon L., Figus A. I., Bajtai A. Chronic gastritis following resection of the stomach. Am J Gastroenterol. 1973 Nov;60(5):477–487. [PubMed] [Google Scholar]
  17. Stempien S. J., Dagradi A. E., Tan D. T. Endoscopic aspects of the gastric mucosa ten years or more after vagotomy-pyloroplasty. Gastrointest Endosc. 1971 Aug;18(1):21–22. doi: 10.1016/s0016-5107(71)74013-9. [DOI] [PubMed] [Google Scholar]
  18. Wall A. J., Ungar B., Baird C. W., Langford I. M., Mackay I. R. Malnutrition after partial gastrectomy. Influence of site of ulcer and type of anastomosis and role of gastritis. Am J Dig Dis. 1967 Nov;12(11):1077–1086. doi: 10.1007/BF02233872. [DOI] [PubMed] [Google Scholar]
  19. Whitehead R., Truelove S. C., Gear M. W. The histological diagnosis of chronic gastritis in fibreoptic gastroscope biopsy specimens. J Clin Pathol. 1972 Jan;25(1):1–11. doi: 10.1136/jcp.25.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. van Heerden J. A., Phillips S. F., Adson M. A., McIlrath D. C. Postoperative reflux gastritis. Am J Surg. 1975 Jan;129(1):82–88. doi: 10.1016/0002-9610(75)90172-5. [DOI] [PubMed] [Google Scholar]

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