Skip to main content
Gut logoLink to Gut
. 1977 Jul;18(7):524–530. doi: 10.1136/gut.18.7.524

Clinical picture of peptic ulceration diagnosed endoscopically.

M C Sheppard, G K Holmes, R Cockel
PMCID: PMC1411572  PMID: 873333

Abstract

Clinical features and laboratory data are presented for 100 patients with benign gastric ulceration and 150 patients with duodenal ulceration confirmed endoscopically in a district general hospital unit. Abdominal pain was the commonest indication for endoscopy, but one third of examinations were performed for acute gastrointestinal haemorrhage. Although the patients were selected by referral for endoscopy their clinical presentation, age, and sex distribution were similar to those reported in previous general surveys. There were no clinical features which clearly distinguished gastric from duodenal ulceration. However, of those with gastric ulceration younger patients more often had distal ulcers and presented with pain, while elderly subjects tended to have high lesser curve involvement and presented with haemorrhage. Moreover, all females presenting with haemorrhage were aged over 50 years, while 6% of males bleeding from gastric ulceration and 40% of males bleeding from duodenal ulceration were under this age. Anaemia when present, except in two premenopausal females, indicated either a recent acute gastrointestinal haemorrhage or a coexistent second diagnosis.

Full text

PDF
529

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BOUDREAU R. P., HARVEY J. P., Jr, ROBBINS S. L. Anatomic study of benign and malignant gastric ulcerations. J Am Med Assoc. 1951 Sep 29;147(5):374–377. doi: 10.1001/jama.1951.03670220014004. [DOI] [PubMed] [Google Scholar]
  2. BRAASCH J. W., CAIN J. C., PRIESTLEY J. T. Juxta-esophageal gastric ulcer. Surg Gynecol Obstet. 1955 Sep;101(3):280–284. [PubMed] [Google Scholar]
  3. Boyle J. D. The Veterans Administration Cooperative Study on Gastric Ulcer. 8. Multiple gastric ulcers. Gastroenterology. 1971 Oct;61(4 Suppl):628–631. [PubMed] [Google Scholar]
  4. Brown P., Salmon P. R., Burwood R. J., Knox A. J., Clendinnen G., Read A. E. The endoscopic, radiological, and surgical findings in chronic duodenal ulceration. Gut. 1973 Nov;14(11):920–920. [PMC free article] [PubMed] [Google Scholar]
  5. Cotton P. B. Fibreoptic endoscopy and the barium meal--results and implications. Br Med J. 1973 Apr 21;2(5859):161–165. doi: 10.1136/bmj.2.5859.161. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Cotton P. B., Rosenberg M. T., Waldram R. P., Axon A. T. Early endoscopy of oesophagus, stomach, and duodenal bulb in patients with haematemesis and melaena. Br Med J. 1973 Jun 2;2(5865):505–509. doi: 10.1136/bmj.2.5865.505. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Davies G. J., Rhodes J., Calcraft B. J. Complications of carbenoxolone therapy. Br Med J. 1974 Aug 10;3(5927):400–402. doi: 10.1136/bmj.3.5927.400. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Edwards F. C., Coghill N. F. Clinical manifestations in patients with chronic atrophic gastritis, gastric ulcer, and duodenal ulcer. Q J Med. 1968 Apr;37(146):337–360. [PubMed] [Google Scholar]
  9. Gainsborough H., Slater E. A Study of Peptic Ulcer. Br Med J. 1946 Aug 24;2(4468):253–258. [PMC free article] [PubMed] [Google Scholar]
  10. JAMIESON R. A., SMITH W. E., SCOTT L. D. W. Peptic ulcer in Glasgow; a hospital survey. Br Med J. 1949 Feb 19;1(4598):298–300. doi: 10.1136/bmj.1.4598.298. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. McColl I. The value of upper gastro-intestinal fibrescopy. Br J Surg. 1972 Oct;59(10):793–794. doi: 10.1002/bjs.1800591012. [DOI] [PubMed] [Google Scholar]
  12. Morrissey J. F. Gastrointestinal endoscopy. Gastroenterology. 1972 Jun;62(6):1241–1268. [PubMed] [Google Scholar]
  13. Mowat N. A., Needham C. K., Brunt P. W. The natural history of gastric ulcer in a community: four-year study. Q J Med. 1975 Jan;44(173):45–56. [PubMed] [Google Scholar]
  14. Nyhus L. M. Gastric ulcer. Scand J Gastroenterol Suppl. 1970;6:123–138. [PubMed] [Google Scholar]
  15. Petrie J. C., Needham C. D., Gillanders L. A. Survey of alimentary radiology findings in the North-east of Scotland Region (1967-70). Br Med J. 1972 Apr 8;2(5805):78–80. doi: 10.1136/bmj.2.5805.78. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Pulvertaft C. N. Comments on the incidence and natural history of gastric and duodenal ulcer. Postgrad Med J. 1968 Aug;44(514):597–602. doi: 10.1136/pgmj.44.514.597. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Rumball J. M. The Veterans Administration Cooperative Study on Gastric Ulcer. 7. Coexistent duodenal ulcer. Gastroenterology. 1971 Oct;61(4 Suppl):622–627. [PubMed] [Google Scholar]
  18. Salmon P. R., Brown P., Htut T., Read A. E. Endoscopic examination of the duodenal bulb: clinical evaluation of forward- and side-viewing fibreoptic systems in 200 cases. Gut. 1972 Mar;13(3):170–175. doi: 10.1136/gut.13.3.170. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Sun D. C., Stempien S. J. The Veterans Administration Cooperative Study on Gastric Ulcer. 3. Site and size of the ulcer as determinants of outcome. Gastroenterology. 1971 Oct;61(4 Suppl):576–584. [PubMed] [Google Scholar]
  20. WATKINSON G. The incidence of chronic peptic ulcer found at necropsy: a study of 20,000 examinations performed in Leeds in 1930-49 and in England and Scotland in 1956. Gut. 1960 Mar;1:14–30. doi: 10.1136/gut.1.1.14. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Winans C. S., Yoshii Y., Kobayashi S. Endoscopic diagnosis of multiple benign gastric ulcers. Gastrointest Endosc. 1972 Nov;19(2):63–66. doi: 10.1016/s0016-5107(72)73954-1. [DOI] [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES