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. 1971 Mar;12(3):218–221. doi: 10.1136/gut.12.3.218

A cross-over comparison of the effect of morphine, pethidine, pentazocine, and phenazocine on biliary pressure

G Economou, J N Ward-McQuaid
PMCID: PMC1411592  PMID: 4928171

Abstract

The effects on biliary pressure of pentazocine, morphine, pethidine, and phenazocine were compared by direct measurement through a `T' tube after choledochotomy. In two within-patient comparisons, the mean increases in biliary pressure following intramuscular morphine were significantly greater than those following pentazocine. When pethidine and phenazocine were compared with pentazocine, the mean increases were lower following pentazocine but not to a statistically significant extent. Pentazocine appears to be the most appropriate strong analgesic in biliary and pancreatic disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Conaghan J. P., Jacobsen M., Rae L., Ward-McQuaid J. N. Pentazocine and phenazocine. A double-blind comparison of two benzomorphan derivatives in postoperative pain. Br J Anaesth. 1966 May;38(5):345–354. doi: 10.1093/bja/38.5.345. [DOI] [PubMed] [Google Scholar]
  2. Danhof I. E. Pentazocine effects on gastrointestinal motor functions in man. Am J Gastroenterol. 1967 Oct;48(4):295–310. [PubMed] [Google Scholar]
  3. Daniel O. A simple method of measuring intra-visceral pressure, of value in uretero-colic anastomosis and study of pressure and flow in the common bile duct. Ir J Med Sci. 1965 Dec;6(480):415–425. doi: 10.1007/BF02976588. [DOI] [PubMed] [Google Scholar]
  4. Daniel O., Singh M. L. Measurement and control of bowel pressure in uretero-colic anastomosis. Br J Urol. 1969 Feb;41(1):32–39. doi: 10.1111/j.1464-410x.1969.tb09905.x. [DOI] [PubMed] [Google Scholar]
  5. EFRON G. Analgesia in pancreatitis with special reference to the effect on pressure in the common bile-duct. S Afr Med J. 1958 Nov 22;32(47):1124–1128. [PubMed] [Google Scholar]
  6. Hinshaw J. R., Hobler K. E., Borja A. R., Sahler C. O. Pentazocine: a potent nonaddicting analgesic. Am J Med Sci. 1966 Jan;251(1):57–62. [PubMed] [Google Scholar]
  7. Hopton D. S., Torrance H. B. Action of various new analgesic drugs on the human common bile duct. Gut. 1967 Jun;8(3):296–300. doi: 10.1136/gut.8.3.296. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. JACOBSSON B. Determination of pressure in the common bile duct at and after operation. Acta Chir Scand. 1957 Oct 12;113(6):483–488. [PubMed] [Google Scholar]
  9. KJELLGREN K., LOF B. Anaesthesia and operative cholangiography. Acta Chir Scand. 1959 Nov 25;118:37–44. [PubMed] [Google Scholar]
  10. KJELLGREN K. Persistence of symptoms following biliary surgery. Ann Surg. 1960 Dec;152:1026–1036. doi: 10.1097/00000658-196012000-00014. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Marth W. Kontinuierliche Elektromanometrie der Gallenwege. Z Gesamte Exp Med. 1968;148(2):108–114. [PubMed] [Google Scholar]

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