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. 1977 Nov;18(11):921–937. doi: 10.1136/gut.18.11.921

Intraepithelial lymphocytes of the small intestine.

A Ferguson
PMCID: PMC1411743  PMID: 338444

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Axton J. H., Chitiyo M. E., Schwartz F. C. Letter: Effect of measles on the intra-epithelial lymphocyte count of malnourished children. S Afr Med J. 1974 Dec 21;48(62):2578–2578. [PubMed] [Google Scholar]
  2. Breucha G., Riethmüller G. Letter: Intestinal lymphocytes in Crohn's disease. Lancet. 1975 Apr 26;1(7913):976–976. doi: 10.1016/s0140-6736(75)92037-1. [DOI] [PubMed] [Google Scholar]
  3. Crabbé P. A., Bazin H., Eyssen H., Heremans J. F. The normal microbial flora as a major stimulus for proliferation of plasma cells synthesizing IgA in the gut. The germ-free intestinal tract. Int Arch Allergy Appl Immunol. 1968;34(4):362–375. doi: 10.1159/000230130. [DOI] [PubMed] [Google Scholar]
  4. Crabbé P. A., Nash D. R., Bazin H., Eyssen D. V., Heremans J. F. Antibodies of the IgA type in intestinal plasma cells of germfree mice after oral or parenteral immunization with ferritin. J Exp Med. 1969 Oct 1;130(4):723–744. doi: 10.1084/jem.130.4.723. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Darlington D., Rogers A. W. Epithelial lymphocytes in the small intestine of the mouse. J Anat. 1966 Oct;100(Pt 4):813–830. [PMC free article] [PubMed] [Google Scholar]
  6. Ecknauer R., Löhrs U. The effect of a single dose of cyclophosphamide on the jejunum of specified pathogenfree and germfree rats. Digestion. 1976;14(3):269–280. doi: 10.1159/000197940. [DOI] [PubMed] [Google Scholar]
  7. Ferguson A., McClure J. P., Townley R. R. Intraepithelial lymphocyte counts in small intestinal biopsies from children with diarrhoea. Acta Paediatr Scand. 1976 Sep;65(5):541–546. doi: 10.1111/j.1651-2227.1976.tb04929.x. [DOI] [PubMed] [Google Scholar]
  8. Ferguson A. Models of intestinal hypersensitivity. Clin Gastroenterol. 1976 May;5(2):271–288. [PubMed] [Google Scholar]
  9. Ferguson A., Murray D. Quantitation of intraepithelial lymphocytes in human jejunum. Gut. 1971 Dec;12(12):988–994. doi: 10.1136/gut.12.12.988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Ferguson A., Parrott D. M. Growth and development of "antigen-free" grafts of foetal mouse intestine. J Pathol. 1972 Feb;106(2):95–101. doi: 10.1002/path.1711060205. [DOI] [PubMed] [Google Scholar]
  11. Ferguson A., Parrott D. M. Histopathology and time course of rejection of allografts of mouse small intestine. Transplantation. 1973 Jun;15(6):546–554. doi: 10.1097/00007890-197306000-00005. [DOI] [PubMed] [Google Scholar]
  12. Ferguson A., Parrott D. M. The effect of antigen deprivation on thymus-dependent and thymus-independent lymphocytes in the small intestine of the mouse. Clin Exp Immunol. 1972 Dec;12(4):477–488. [PMC free article] [PubMed] [Google Scholar]
  13. Ferguson R., Allan R. N., Cooke W. T. A study of the cellular infiltrate of the proximal jejunal mucosa in ulcerative colitis and Crohn's disease. Gut. 1975 Mar;16(3):205–208. doi: 10.1136/gut.16.3.205. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Ferguson R., Asquith P., Cooke W. T. The jejunal cellular infiltrate in coeliac disease complicated by lymphoma. Gut. 1974 Jun;15(6):458–461. doi: 10.1136/gut.15.6.458. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Fichtelius K. E. Cellular aspects on the phylogeny of immunity. Lymphology. 1970 Mar;3(1):50–59. [PubMed] [Google Scholar]
  16. Fichtelius K. E., Jaroslow B. N. Changes in the concentration of lymphocytes in the intestinal epithelium of hibernating ground squirrels (Citellus tridecemlineatus). Acta Pathol Microbiol Scand. 1969;77(1):99–102. doi: 10.1111/j.1699-0463.1969.tb04211.x. [DOI] [PubMed] [Google Scholar]
  17. Fichtelius K. E., Lidén S., Groth O. The skin--a first level lymphoid organ? Int Arch Allergy Appl Immunol. 1971;41(1):13–15. doi: 10.1159/000230480. [DOI] [PubMed] [Google Scholar]
  18. Fichtelius K. E. Radiosensitivity of the lymphocytes within the gut epithelium. Acta Pathol Microbiol Scand. 1969;75(1):27–32. [PubMed] [Google Scholar]
  19. Fichtelius K. E., Sundström C., Kullgren B., Linna J. The lympho-epithelial organs of Homo sapiens revisited. Acta Pathol Microbiol Scand. 1969;77(1):103–116. doi: 10.1111/j.1699-0463.1969.tb04212.x. [DOI] [PubMed] [Google Scholar]
  20. Fichtelius K. E. The gut epithelium--a first level lymphoid organ? Exp Cell Res. 1968 Jan;49(1):87–104. doi: 10.1016/0014-4827(68)90522-3. [DOI] [PubMed] [Google Scholar]
  21. Fichtelius K. E. The mammalian equivalent to bursa Fabricii of birds. Exp Cell Res. 1967 Apr;46(1):231–234. doi: 10.1016/0014-4827(67)90427-2. [DOI] [PubMed] [Google Scholar]
  22. Fichtelius K. E., Yunis E. J., Good R. A. Occurrence of lymphocytes within the gut epithelium of normal and neonatally thymectomized mice. Proc Soc Exp Biol Med. 1968 May;128(1):185–188. doi: 10.3181/00379727-128-32974. [DOI] [PubMed] [Google Scholar]
  23. Fry L., Seah P. P., Harper P. G., Hoffbrand A. V., McMinn R. M. The small intestine in dermatitis herpetiformis. J Clin Pathol. 1974 Oct;27(10):817–824. doi: 10.1136/jcp.27.10.817. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Fry L., Seah P. P., McMinn R. M., Hoffbrand A. V. Lymphocytic infiltration of epithelium in diagnosis of gluten-sensitive enteropathy. Br Med J. 1972 Aug 12;3(5823):371–374. doi: 10.1136/bmj.3.5823.371. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. GOWANS J. L., KNIGHT E. J. THE ROUTE OF RE-CIRCULATION OF LYMPHOCYTES IN THE RAT. Proc R Soc Lond B Biol Sci. 1964 Jan 14;159:257–282. doi: 10.1098/rspb.1964.0001. [DOI] [PubMed] [Google Scholar]
  26. Glaister J. R. Autoradiographic studies of lymphoid cells in the small intestinal epithelium of the mouse. Int Arch Allergy Appl Immunol. 1973;45(6):844–853. doi: 10.1159/000231084. [DOI] [PubMed] [Google Scholar]
  27. Glaister J. R. Factors affecting the lymphoid cells in the small intestinal epithelium of the mouse. Int Arch Allergy Appl Immunol. 1973;45(5):719–730. doi: 10.1159/000231071. [DOI] [PubMed] [Google Scholar]
  28. Glaister J. R. Light, fluorescence and electron microscopic studies of lymphoid cells in the small intestinal epithelium of mice. Int Arch Allergy Appl Immunol. 1973;45(6):854–867. doi: 10.1159/000231085. [DOI] [PubMed] [Google Scholar]
  29. Glaister J. R. Some effects of oral administration of oxazolone to mice. Int Arch Allergy Appl Immunol. 1973;45(6):828–843. doi: 10.1159/000231083. [DOI] [PubMed] [Google Scholar]
  30. Goldschneider I., McGregor D. D. Migration of lymphocytes and thymocytes in the rat. I. The route of migration from blood to spleen and lymph nodes. J Exp Med. 1968 Jan 1;127(1):155–168. doi: 10.1084/jem.127.1.155. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Guy-Grand D., Griscelli C., Vassalli P. The gut-associated lymphoid system: nature and properties of the large dividing cells. Eur J Immunol. 1974 Jun;4(6):435–443. doi: 10.1002/eji.1830040610. [DOI] [PubMed] [Google Scholar]
  32. Hall J. G., Smith M. E. Homing of lymph-borne immunoblasts to the gut. Nature. 1970 Apr 18;226(5242):262–263. doi: 10.1038/226262a0. [DOI] [PubMed] [Google Scholar]
  33. Halstead T. E., Hall J. G. The homing of lymph-borne immunoblasts to the small gut of neonatal rats. Transplantation. 1972 Sep;14(3):339–346. doi: 10.1097/00007890-197209000-00009. [DOI] [PubMed] [Google Scholar]
  34. Holmes G. K., Asquith P., Stokes P. L., Cooke W. T. Cellular infiltrate of jejunal biopsies in adult coeliac disease in relation to gluten withdrawal. Gut. 1974 Apr;15(4):278–283. [PMC free article] [PubMed] [Google Scholar]
  35. Kuitunen P., Rapola J., Savilahti E., Visakorpi J. K. Response of the jejunal mucosa to cow's milk in the malabsorption syndrome with cow's milk intolerance. A light- and electron-microscopic study. Acta Paediatr Scand. 1973 Nov;62(6):585–595. doi: 10.1111/j.1651-2227.1973.tb17069.x. [DOI] [PubMed] [Google Scholar]
  36. Kumar P. J., Ferguson A., Lancaster-Smith M., Clark M. L. Food antibodies in patients with dermatitis herpetiformis and adult coeliac disease - relationship to jejunal morphology. Scand J Gastroenterol. 1976;11(1):5–9. [PubMed] [Google Scholar]
  37. Kumar P. J., Silk D. B., Marks R., Clark M. L., Dawson A. M. Treatment of dermatitis herpetiformis with corticosteroids and a gluten-free diet: a study of jejunal morphology and function. Gut. 1973 Apr;14(4):280–283. doi: 10.1136/gut.14.4.280. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Laissue J. A., Chanana A. D., Cottier H., Cronkite E. P., Joel D. D. Fate of intraintestinal thymocytes labeled with 125iododeoxyuridine or tritiated thymidine. Proc Soc Exp Biol Med. 1976 Jun;152(2):262–265. doi: 10.3181/00379727-152-39375. [DOI] [PubMed] [Google Scholar]
  39. Lancaster-Smith M., Kumar P. J., Dawson A. M. The cellular infiltrate of the jejunum in adult coeliac disease and dermatitis herpetiformis following the reintroduction of dietary gluten. Gut. 1975 Sep;16(9):683–688. doi: 10.1136/gut.16.9.683. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Lancaster-Smith M., Packer S., Kumar P. J., Harries J. T. Cellular infiltrate of the jejunum after re-introduction of dietary gluten in children with treated coeliac disease. J Clin Pathol. 1976 Jul;29(7):587–591. doi: 10.1136/jcp.29.7.587. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Lemmel E. M., Fichtelius K. E. Life span of lymphocytes within intestinal epithelium, Peyer's patch epithelium, epidermis, and liver of mice. Int Arch Allergy Appl Immunol. 1971;41(5):716–728. doi: 10.1159/000230563. [DOI] [PubMed] [Google Scholar]
  42. MacDonald T. T., Ferguson A. Hypersensitivity reactions in the small intestine. 2. Effects of allograft rejection on mucosal architecture and lymphoid cell infiltrate. Gut. 1976 Feb;17(2):81–91. doi: 10.1136/gut.17.2.81. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. MacDonald T. T., Ferguson A. Hypersensitivity reactions in the small intestine. III. The effects of allograft rejection and of graft-versus-host disease on epithelial cell kinetics. Cell Tissue Kinet. 1977 Jul;10(4):301–312. [PubMed] [Google Scholar]
  44. Marsh M. N. Studies of intestinal lymphoid tissue. I. Electron microscopic evidence of 'blast transformation' in epithelial lymphocytes of mouse small intestinal mucosa. Gut. 1975 Sep;16(9):665–674. doi: 10.1136/gut.16.9.665. [DOI] [PMC free article] [PubMed] [Google Scholar]
  45. Marsh M. N. Studies of intestinal lymphoid tissue. II. Aspects of proliferation and migration of epithelial lymphocytes in the small intestine of mice. Gut. 1975 Sep;16(9):674–682. doi: 10.1136/gut.16.9.674. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Mattioli C. A., Tomasi T. B., Jr The life span of IgA plasma cells from the mouse intestine. J Exp Med. 1973 Aug 1;138(2):452–460. doi: 10.1084/jem.138.2.452. [DOI] [PMC free article] [PubMed] [Google Scholar]
  47. Mavromichalis J., Brueton M. J., McNeish A. S., Anderson C. M. Evaluation of the intraepithelial lymphocyte count in the jejunum in childhood enteropathies. Gut. 1976 Aug;17(8):600–603. doi: 10.1136/gut.17.8.600. [DOI] [PMC free article] [PubMed] [Google Scholar]
  48. McNicholl B., Egan-Mitchell B., Stevens F., Keane R., Baker S., McCarthy C. F., Fottrell P. F. Mucosal recovery in treated childhood celiac disease (gluten-sensitive enteropathy). J Pediatr. 1976 Sep;89(3):418–424. doi: 10.1016/s0022-3476(76)80539-2. [DOI] [PubMed] [Google Scholar]
  49. Meader R. D., Landers D. F. Electron and light microscopic observations on relationships between lymphocytes and intestinal epithelium. Am J Anat. 1967 Nov;121(3):763–773. doi: 10.1002/aja.1001210318. [DOI] [PubMed] [Google Scholar]
  50. Meuwissen S. G., Feltkamp-Vroom T. M., De La Rivière A. B., Von Dem Borne A. E., Tytgat G. N. Analysis of the lympho-plasmacytic infiltrate in Crohn's disease with special reference to identification of lymphocyte-subpopulations. Gut. 1976 Oct;17(10):770–780. doi: 10.1136/gut.17.10.770. [DOI] [PMC free article] [PubMed] [Google Scholar]
  51. Montgomery R. D., Shearer A. C. The cell population of the upper jejunal mucosa in tropical sprue and postinfective malabsorption. Gut. 1974 May;15(5):387–391. doi: 10.1136/gut.15.5.387. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Moore A. R., Hall J. G. Evidence for a primary association between immunoblasts and small gut. Nature. 1972 Sep 15;239(5368):161–162. doi: 10.1038/239161a0. [DOI] [PubMed] [Google Scholar]
  53. O'Donoghue D. P., Lancaster-Smith M., Laviniere P., Kumar P. J. T cell depletion in untreated adult coeliac disease. Gut. 1976 May;17(5):328–331. doi: 10.1136/gut.17.5.328. [DOI] [PMC free article] [PubMed] [Google Scholar]
  54. Otto H. F. The interepithelial lymphocytes of the intestinum. Morphological observations and immunologic aspects of intestinal enteropathy. Curr Top Pathol. 1973;57:81–121. doi: 10.1007/978-3-642-65465-7_3. [DOI] [PubMed] [Google Scholar]
  55. Otto H. F., Walke A. Uber lympho-epitheliale Beziehungen bei Enteropathien. Virchows Arch A Pathol Pathol Anat. 1972;355(1):85–98. [PubMed] [Google Scholar]
  56. Owen R. L., Jones A. L. Epithelial cell specialization within human Peyer's patches: an ultrastructural study of intestinal lymphoid follicles. Gastroenterology. 1974 Feb;66(2):189–203. [PubMed] [Google Scholar]
  57. Parrott D. M., Ferguson A. Selective migration of lymphocytes within the mouse small intestine. Immunology. 1974 Mar;26(3):571–588. [PMC free article] [PubMed] [Google Scholar]
  58. Parrott D. M., Tilney N. L., Sless F. The different migratory characteristics of lymphocyte populations from a whole spleen transplant. Clin Exp Immunol. 1975 Mar;19(3):459–474. [PMC free article] [PubMed] [Google Scholar]
  59. Pink I. J., Croft D. N., Creamer B. Cell loss from small intestinal mucosa: a morphological study. Gut. 1970 Mar;11(3):217–222. doi: 10.1136/gut.11.3.217. [DOI] [PMC free article] [PubMed] [Google Scholar]
  60. Rose M. L., Parrott D. M., Bruce R. G. I. Effect of Trichinella spiralis infection on the migration of mesenteric lymphoblasts and mesenteric T lymphoblasts in syngeneic mice. Immunology. 1976 Nov;31(5):723–730. [PMC free article] [PubMed] [Google Scholar]
  61. Rudzik O., Bienenstock J. Isolation and characteristics of gut mucosal lymphocytes. Lab Invest. 1974 Mar;30(3):260–266. [PubMed] [Google Scholar]
  62. Rudzik O., Clancy R. L., Perey D. Y., Bienenstock J., Singal D. P. The distribution of a rabbit thymic antigen and membrane immunoglobulins in lymphoid tissue, with special reference to mucosal lymphocytes. J Immunol. 1975 Jan;114(1 Pt 1):1–4. [PubMed] [Google Scholar]
  63. Röpke C., Everett N. B. Kinetics of intraepithelial lymphocytes in the small intestine of thymus-deprived mice and antigen-deprived mice. Anat Rec. 1976 May;185(1):101–108. doi: 10.1002/ar.1091850110. [DOI] [PubMed] [Google Scholar]
  64. Röpke C., Everett N. B. Proliferative kinetics of large and small intraepithelial lymphocytes in the small intestine of the mouse. Am J Anat. 1976 Mar;145(3):395–408. doi: 10.1002/aja.1001450307. [DOI] [PubMed] [Google Scholar]
  65. Schaad U., Gaze H., Hadorn B., Pedrinis E., Cottier H., Lorenz E., Colombo J. P. Der Blutxylosetest im Kindesalter: Korrelation des 1-Stunden-Blutxylosewertes mit der Anzahl intraepithelial gelegener Lymphozyten in der Dünndarmschleimhaut bei der Zöliakie. Helv Paediatr Acta. 1976 Jan;30(4-5):331–341. [PubMed] [Google Scholar]
  66. Schwartz F. C., Chitiyo M. E., Wolfsdorf J. Letter: Intra-epithelial lymphocytes in the jejunum of malnourished children. S Afr Med J. 1974 Oct 19;48(51):2128–2128. [PubMed] [Google Scholar]
  67. Singal D. P., O'Neill M., Clancy R., Bienenstock J. Functional T cells in rabbits gut mucosal lymphocytes. Gut. 1976 May;17(5):325–327. doi: 10.1136/gut.17.5.325. [DOI] [PMC free article] [PubMed] [Google Scholar]
  68. Skinner J. M., Whitehead R. Morphological methods in the study of the gut immune system in man. J Clin Pathol. 1976 Jun;29(6):564–567. doi: 10.1136/jcp.29.6.564. [DOI] [PMC free article] [PubMed] [Google Scholar]
  69. Stevens F. M., Lloyd R., Egan-Mitchell B., Mylotte M. J., Fottrell P. F., Wright R., McNicholl B., McCarthy C. F. Reticulin antibodies in patients with coeliac disease and their relatives. Gut. 1975 Aug;16(8):598–602. doi: 10.1136/gut.16.8.598. [DOI] [PMC free article] [PubMed] [Google Scholar]
  70. Strickland R. G., Husby G., Black W. C., Williams R. C., Jr Peripheral blood and intestinal lymphocyte sub-populations in Crohn's disease. Gut. 1975 Nov;16(11):847–853. doi: 10.1136/gut.16.11.847. [DOI] [PMC free article] [PubMed] [Google Scholar]
  71. Toner P. G., Ferguson A. Intraepithelial cells in the human intestinal mucosa. J Ultrastruct Res. 1971 Feb;34(3):329–344. doi: 10.1016/s0022-5320(71)80076-x. [DOI] [PubMed] [Google Scholar]

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