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. 1972 Mar;13(3):176–181. doi: 10.1136/gut.13.3.176

Gastric emptying of solid meals after truncal vagotomy and pyloroplasty in human subjects

D J Cowley, P Vernon, T Jones, H I Glass, A G Cox
PMCID: PMC1412129  PMID: 5024721

Abstract

Gastric emptying of isotopically labelled solid meals was studied in normal human subjects and in patients at different intervals after truncal vagotomy and Heineke-Mikulicz pyloroplasty.

One to four weeks after vagotomy and pyloroplasty gastric emptying was delayed grossly in some patients regardless of the completeness of vagotomy. Patients with gross delay had symptoms of gastric retention. Eight weeks later emptying had returned towards normal and one or more years after vagotomy and pyloroplasty emptying was within the normal range.

A subthreshold dose of carbachol injected during the course of emptying of a meal in some of the postvagotomy patients had no detectable influence on the rate of emptying of the meal.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Barnes A. D., Williams J. A. Stomach drainage after vagotomy and pyloroplasty. Am J Surg. 1967 Apr;113(4):494–497. doi: 10.1016/0002-9610(67)90194-8. [DOI] [PubMed] [Google Scholar]
  2. Buckler K. G. Effects of gastric surgery upon gastric emptying in cases of peptic ulceration. Gut. 1967 Apr;8(2):137–147. doi: 10.1136/gut.8.2.137. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Dragstedt L. R., Harper P. V., Tovee E. B., Woodward E. R. Section of the Vagus Nerves to the Stomach in the Treatment of Peptic Ulcer : Complications and End Results After Four Years. Ann Surg. 1947 Nov;126(5):687–699. [PMC free article] [PubMed] [Google Scholar]
  4. Griffith G. H., Owen G. M., Kirkman S., Shields R. Measurement of rate of gastric emptying using chromium-51. Lancet. 1966 Jun 4;1(7449):1244–1245. doi: 10.1016/s0140-6736(66)90247-9. [DOI] [PubMed] [Google Scholar]
  5. Jones T., Clark J. C., Kocak N., Cox A. G., Glass H. I. Measurement of gastric emptying using the scintillation camera and 129Cs. Br J Radiol. 1970 Aug;43(512):537–541. doi: 10.1259/0007-1285-43-512-537. [DOI] [PubMed] [Google Scholar]
  6. McKelvey S. T., Connell A. M., Kennedy T. L. Gastric emptying and transit time as factors in postvagotomy diarrhea. Gut. 1969 Dec;10(12):1047–1047. [PubMed] [Google Scholar]
  7. Tinker J., Kocak N., Jones T., Glass H. I., Cox A. G. Supersensitivity and gastric emptying after vagotomy. Gut. 1970 Jun;11(6):502–505. doi: 10.1136/gut.11.6.502. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Vernon P., Glass H. I. An off-line digital system for use with a gamma camera. Phys Med Biol. 1971 Jul;16(3):405–415. doi: 10.1088/0031-9155/16/3/002. [DOI] [PubMed] [Google Scholar]

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