Skip to main content
Gut logoLink to Gut
. 1972 Dec;13(12):1000–1013. doi: 10.1136/gut.13.12.1000

Carcinoembryonic antigen (CEA).

P W Dykes, J King
PMCID: PMC1412499  PMID: 4119804

Full text

PDF
1003

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Butin P., Martin E., Sabine M. C., von Kleist S. Immunological study of polyps of the colon. J Natl Cancer Inst. 1972 Jan;48(1):25–32. [PubMed] [Google Scholar]
  2. Chu T. M., Reynoso G., Hansen H. J. Demonstration of carcinoembryonic antigen in normal human plasma. Nature. 1972 Jul 21;238(5360):152–153. doi: 10.1038/238152a0. [DOI] [PubMed] [Google Scholar]
  3. Coligan J. E., Lautenschleger J. T., Egan M. L., Todd C. W. Isolation and characterization of carcinoembryonic antigen. Immunochemistry. 1972 Apr;9(4):377–386. doi: 10.1016/0019-2791(72)90308-4. [DOI] [PubMed] [Google Scholar]
  4. Collatz E., Von Kleist S., Burtin P. Further investigations of circulating antibodies in colon cancer patients: on the autoantigenicity of the carcinoembryonic antigen. Int J Cancer. 1971 Sep 15;8(2):298–303. doi: 10.1002/ijc.2910080215. [DOI] [PubMed] [Google Scholar]
  5. Collins J. J., Black P. H. Specificity of the carcinoembryonic antigen (CEA). N Engl J Med. 1971 Jul 15;285(3):175–176. doi: 10.1056/NEJM197107152850313. [DOI] [PubMed] [Google Scholar]
  6. Darcy D. A. A general method of increasing the sensitivity of immune diffusion. Its application to CEA. Clin Chim Acta. 1972 May;38(2):329–337. doi: 10.1016/0009-8981(72)90123-4. [DOI] [PubMed] [Google Scholar]
  7. Devroede G. J., Taylor W. F., Sauer W. G., Jackman R. J., Stickler G. B. Cancer risk and life expectancy of children with ulcerative colitis. N Engl J Med. 1971 Jul 1;285(1):17–21. doi: 10.1056/NEJM197107012850103. [DOI] [PubMed] [Google Scholar]
  8. Dhar P., Moore T., Zamcheck N., Kupchik H. Z. Carcinoembryonic antigen (CEA) in colonic cancer. Use in preoperative and postoperative diagnosis and prognosis. JAMA. 1972 Jul 3;221(1):31–35. [PubMed] [Google Scholar]
  9. Egan M. L., Lautenschleger J. T., Coligan J. E., Todd C. W. Radioimmune assay of carcinoembryonic antigen. Immunochemistry. 1972 Mar;9(3):289–299. doi: 10.1016/0019-2791(72)90093-6. [DOI] [PubMed] [Google Scholar]
  10. Freed D. L., Taylor G. Carcinoembryonic antigen in faeces. Br Med J. 1972 Jan 8;1(5792):85–87. doi: 10.1136/bmj.1.5792.85. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Freedman S. O., Gold P., Krupey J., Machado H. da C. Human tumour antigens. Proc Can Cancer Conf. 1969;8:407–424. [PubMed] [Google Scholar]
  12. GOLD P., FREEDMAN S. O. DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES. J Exp Med. 1965 Mar 1;121:439–462. doi: 10.1084/jem.121.3.439. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Gold J. M., Freedman S. O., Gold P. Human anti-CEA antibodies detected by radioimmunoelectrophoresis. Nat New Biol. 1972 Sep 13;239(89):60–62. doi: 10.1038/newbio239060a0. [DOI] [PubMed] [Google Scholar]
  14. Gold P., Freedman S. O. Specific carcinoembryonic antigens of the human digestive system. J Exp Med. 1965 Sep 1;122(3):467–481. doi: 10.1084/jem.122.3.467. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Gold P., Krupey J., Ansari H. Position of the carcinoembryonic antigen of the human digestive system in ultrastructure of tumor cell surface. J Natl Cancer Inst. 1970 Aug;45(2):219–225. [PubMed] [Google Scholar]
  16. Goldenberg D. M., Tchilinguirian N. G., Hansen H. J., Vandevoorde J. P. Carcinoembryonic antigen present in meconium: the basis of a possible new diagnostic test of fetal distress. Am J Obstet Gynecol. 1972 May 1;113(1):66–69. doi: 10.1016/0002-9378(72)90453-x. [DOI] [PubMed] [Google Scholar]
  17. Hall R. R., Laurence D. J., Darcy D., Stevens U., James R., Roberts S., Munro Neville A. Carcinoembryonic antigen in the urine of patients with urothelial carcinoma. Br Med J. 1972 Sep 9;3(5827):609–611. doi: 10.1136/bmj.3.5827.609. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Hellström I., Hellström K. E. Newer concepts of cancer of the colon and rectum: cellular immunity to human colonic carcinomas. Dis Colon Rectum. 1972 Mar-Apr;15(2):100–105. doi: 10.1007/BF02587253. [DOI] [PubMed] [Google Scholar]
  19. Hellström I., Hellström K. E., Pierce G. E., Yang J. P. Cellular and humoral immunity to different types of human neoplasms. Nature. 1968 Dec 28;220(5174):1352–1354. doi: 10.1038/2201352a0. [DOI] [PubMed] [Google Scholar]
  20. Hellström I., Hellström K. E., Shepard T. H. Cell-mediated immunity against antigens common to human colonic carcinomas and fetal gut epithelium. Int J Cancer. 1970 Nov 15;6(3):346–351. doi: 10.1002/ijc.2910060304. [DOI] [PubMed] [Google Scholar]
  21. Hellström I., Sjögren H. O., Warner G., Hellström K. E. Blocking of cell-mediated tumor immunity by sera from patients with growing neoplasms. Int J Cancer. 1971 Mar 15;7(2):226–237. doi: 10.1002/ijc.2910070206. [DOI] [PubMed] [Google Scholar]
  22. Hollinshead A., Glew D., Bunnag B., Gold P., Herberman R. Skin-reactive soluble antigen from intestinal cancer-cell-membranes and relationship to carcinoembryonic antigens. Lancet. 1970 Jun 6;1(7658):1191–1195. doi: 10.1016/s0140-6736(70)91784-8. [DOI] [PubMed] [Google Scholar]
  23. Kleinman M. S., Harwell L., Turner M. D. Studies of colonic carcinoma antigens. Gut. 1971 Jan;12(1):1–10. doi: 10.1136/gut.12.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Kleinman M. S., Turner M. D. Radioimmunoassay of carcinoembryonic antigen in serum of normal subjects and patients with colonic carcinoma. Gut. 1972 May;13(5):390–394. doi: 10.1136/gut.13.5.390. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Kronman B. S., Shapiro H. M., Localio S. A. Newer concepts of cancer of the colon and rectum: delayed hypersensitivity responses of patients with carcinoma of the colon and other solid tumors. Dis Colon Rectum. 1972 Mar-Apr;15(2):106–110. doi: 10.1007/BF02587255. [DOI] [PubMed] [Google Scholar]
  26. Krupey J., Gold P., Freedman S. O. Physicochemical studies of the carcinoembryonic antigens of the human digestive system. J Exp Med. 1968 Sep 1;128(3):387–398. doi: 10.1084/jem.128.3.387. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Krupey J., Gold P., Freedman S. O. Purification and characterization of carcinoembryonic antigens of the human digestive system. Nature. 1967 Jul 1;215(5096):67–68. doi: 10.1038/215067a0. [DOI] [PubMed] [Google Scholar]
  28. Krupey J., Wilson T., Freedman S. O., Gold P. The preparation of purified carcinoembryonic antigen of the human digestive system from large quantities of tumor tissue. Immunochemistry. 1972 Jun;9(6):617–622. doi: 10.1016/0019-2791(72)90247-9. [DOI] [PubMed] [Google Scholar]
  29. Kupchik H. Z., Zamcheck N. Carcinoembryonic antigen(s) in liver disease. II. Isolation from human cirrhotic liver and serum and from normal liver. Gastroenterology. 1972 Jul;63(1):95–101. [PubMed] [Google Scholar]
  30. Laurence D. J., Stevens U., Bettelheim R., Darcy D., Leese C., Turberville C., Alexander P., Johns E. W., Neville A. M. Role of plasma carcinoembryonic antigen in diagnosis of gastrointestinal, mammary, and bronchial carcinoma. Br Med J. 1972 Sep 9;3(5827):605–609. doi: 10.1136/bmj.3.5827.605. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. LeBel J. S., Deodhar S. D., Brown C. H. Newer concepts of cancer of the colon and rectum: clinical evaluation of a radioimmunoassay for CEA. Dis Colon Rectum. 1972 Mar-Apr;15(2):111–115. doi: 10.1007/BF02587256. [DOI] [PubMed] [Google Scholar]
  32. Lejtenyi M. C., Freedman S. O., Gold P. Response of lymphocytes from patients with gastrointestinal cancer to the carcinoembryonic antigen of the human digestive system. Cancer. 1971 Jul;28(1):115–120. doi: 10.1002/1097-0142(197107)28:1<115::aid-cncr2820280121>3.0.co;2-k. [DOI] [PubMed] [Google Scholar]
  33. Lo Gerfo P., Herter F. P., Bennett S. J. Absence of circulating antibodies to carcinoembryonic antigen in patients with gastrointestinal malignancies. Int J Cancer. 1972 Mar 15;9(2):344–348. doi: 10.1002/ijc.2910090212. [DOI] [PubMed] [Google Scholar]
  34. Lo Gerfo P., Herter F. P., Bennett S. J. Absence of circulating antibodies to carcinoembryonic antigen in patients with gastrointestinal malignancies. Int J Cancer. 1972 Mar 15;9(2):344–348. doi: 10.1002/ijc.2910090212. [DOI] [PubMed] [Google Scholar]
  35. Lo Gerfo P., Herter F. P., Braun J., Hansen H. J. Tumor associated antigen with pulmonary neoplasms. Ann Surg. 1972 Apr;175(4):495–500. doi: 10.1097/00000658-197204000-00006. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Lo Gerfo P., Krupey J., Hansen H. J. Demonstration of an antigen common to several varieties of neoplasia. N Engl J Med. 1971 Jul 15;285(3):138–141. doi: 10.1056/NEJM197107152850302. [DOI] [PubMed] [Google Scholar]
  37. Lo Gerfo P., Lo Gerfo F., Herter F., Barker H. G., Hansen H. J. Tumor-associated antigen in patients with carcinoma of the colon. Am J Surg. 1972 Feb;123(2):127–131. doi: 10.1016/0002-9610(72)90321-2. [DOI] [PubMed] [Google Scholar]
  38. Mach J. P., Pusztaszeri G. Carcinoembryonic antigen (CEA): demonstration of a partial identity between CEA and a normal glycoprotein. Immunochemistry. 1972 Oct;9(10):1031–1034. doi: 10.1016/0019-2791(72)90113-9. [DOI] [PubMed] [Google Scholar]
  39. Martin F., Martin M. S., Bordes M., Bourgeaux C. The specificity of carcino-foetal antigens of the human digestive-tract tumours. Eur J Cancer. 1972 Jun;8(3):315–321. doi: 10.1016/0014-2964(72)90027-8. [DOI] [PubMed] [Google Scholar]
  40. Martin F., Martin M. S. Demonstration of antigens related to colonic cancer in the human digestive system. Int J Cancer. 1970 Nov 15;6(3):352–360. doi: 10.1002/ijc.2910060305. [DOI] [PubMed] [Google Scholar]
  41. Martin F., Martin M. S. Radioimmunoassay of carcinoembryonic antigen in extracts of human colon and stomach. Int J Cancer. 1972 May 15;9(3):641–647. doi: 10.1002/ijc.2910090322. [DOI] [PubMed] [Google Scholar]
  42. Moore T. L., Kupchik H. Z., Marcon N., Zamcheck N. Carcinoembryonic antigen assay in cancer of the colon and pancreas and other digestive tract disorders. Am J Dig Dis. 1971 Jan;16(1):1–7. doi: 10.1007/BF02233781. [DOI] [PubMed] [Google Scholar]
  43. Moore T., Dhar P., Zamcheck N., Keeley A., Gottlieb L., Kupchik H. Z. Carcinoembryonic antigen(s) in liver disease. I. Clinical and morphological studies. Gastroenterology. 1972 Jul;63(1):88–94. [PubMed] [Google Scholar]
  44. Morson B. C., Pang L. S. Rectal biopsy as an aid to cancer control in ulcerative colitis. Gut. 1967 Oct;8(5):423–434. doi: 10.1136/gut.8.5.423. [DOI] [PMC free article] [PubMed] [Google Scholar]
  45. Odili J. L., Taylor G. Transience of immune responses to tumour antigens in man. Br Med J. 1971 Dec 4;4(5787):584–586. doi: 10.1136/bmj.4.5787.584. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Reynoso G., Chu T. M., Holyoke D., Cohen E., Nemoto T., Wang J. J., Chuang J., Guinan P., Murphy G. P. Carcinoembryonic antigen in patients with different cancers. JAMA. 1972 Apr 17;220(3):361–365. [PubMed] [Google Scholar]
  47. Rule A. H., Straus E., Vandevoorde J., Janowitz H. D. Tumor-associated (CEA-reacting) antigen in patients with inflammatory bowel disease. N Engl J Med. 1972 Jul 6;287(1):24–26. doi: 10.1056/NEJM197207062870106. [DOI] [PubMed] [Google Scholar]
  48. Rule A. H., Straus E., Vandevoorde J., Janowitz H. D. Tumor-associated (CEA-reacting) antigen in patients with inflammatory bowel disease. N Engl J Med. 1972 Jul 6;287(1):24–26. doi: 10.1056/NEJM197207062870106. [DOI] [PubMed] [Google Scholar]
  49. Sjögren H. O., Hellström I., Bansal S. C., Hellström K. E. Suggestive evidence that the "blocking antibodies" of tumor-bearing individuals may be antigen--antibody complexes. Proc Natl Acad Sci U S A. 1971 Jun;68(6):1372–1375. doi: 10.1073/pnas.68.6.1372. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. Sjögren H. O., Hellström I., Bansal S. C., Warner G. A., Hellström K. E. Elution of "blocking factors" from human tumors, capable of abrogating tumor-cell destruction by specifically immune lymphocytes. Int J Cancer. 1972 Mar 15;9(2):274–283. doi: 10.1002/ijc.2910090205. [DOI] [PubMed] [Google Scholar]
  51. Terry W. D., Henkart P. A., Coligan J. E., Todd C. W. Structural studies of the major glycoprotein in preparations with carcinoembryonic antigen activity. J Exp Med. 1972 Jul 1;136(1):200–204. doi: 10.1084/jem.136.1.200. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Thomson D. M., Krupey J., Freedman S. O., Gold P. The radioimmunoassay of circulating carcinoembryonic antigen of the human digestive system. Proc Natl Acad Sci U S A. 1969 Sep;64(1):161–167. doi: 10.1073/pnas.64.1.161. [DOI] [PMC free article] [PubMed] [Google Scholar]
  53. Turner M. D., Olivares T. A., Harwell L., Kleinman M. S. Further purification of perchlorate-soluble antigens from human colonic carcinomata. J Immunol. 1972 May;108(5):1328–1339. [PubMed] [Google Scholar]
  54. von Kleist S., Burtin P. Isolation of a fetal antigen from human colonic tumors. Cancer Res. 1969 Nov;29(11):1961–1964. [PubMed] [Google Scholar]
  55. von Kleist S., Burtin P. Localisation cellulaire d'un antigène embryonnaire de tumeurs coliques humaines. Int J Cancer. 1969 Nov 15;4(6):874–879. doi: 10.1002/ijc.2910040616. [DOI] [PubMed] [Google Scholar]
  56. von Kleist S., Burtin P. On the specificity of autoantibodies present in colon cancer patients. Immunology. 1966 Jun;10(6):507–515. [PMC free article] [PubMed] [Google Scholar]
  57. von Kleist S., Chavanel G., Burtin P. Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen. Proc Natl Acad Sci U S A. 1972 Sep;69(9):2492–2494. doi: 10.1073/pnas.69.9.2492. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES