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. 1973 Jul;14(7):545–548. doi: 10.1136/gut.14.7.545

Studies of carcinoembryonic antigen of whole and extracted serum in ulcerative colitis

S K Khoo, P S Hunt, I R Mackay
PMCID: PMC1412801  PMID: 4354145

Abstract

The present study has used a microradioimmunoassay to detect carcinoembryonic antigen(s) (CEA) in whole and extracted serum in 77 patients with ulcerative colitis, two of whom had coexisting colonic carcinoma, and 69 patients with carcinoma of the colon or rectum. Taking 5 ng/ml as the level of positivity, the CEA assay on whole serum showed positive results in patients with `active' ulcerative colitis (15 of 17) but not in those with `inactive' disease (0 of 23). In two patients, levels fell during drug-induced remission. Our results also indicated that a positive result for CEA on extracted serum was associated with carcinomatous changes in ulcerative colitis in contrast to uncomplicated ulcerative colitis in which positive results were obtained only with whole serum.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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