Skip to main content
PMC home page
Gut logoLink to Gut
. 1960 Mar;1(1):55–61. doi: 10.1136/gut.1.1.55

A Study of the Pancreatic Response to Food after Gastrectomy in Man *

T J Butler
PMCID: PMC1413135  PMID: 13806516

Abstract

The results of intubation tests on 50 patients before and after gastrectomy have been reviewed. Following gastrectomy, the pancreatic response to food is modified in the following manner.

(1) There is an increase in the resting volume of secretion.

(2) After a Billroth I operation, the output in one hour after a meal is some two-thirds of the pre-operative output.

(3) After a Polya gastrectomy, the pancreas continues to secrete at its resting rate after meals.

(4) Dissociation of enzymes occurs in the afferent loop after a Polya operation. Lipase is frequently absent from the intestinal contents, and trypsin occasionally so.

(5) Vagal section appears to be an important factor in the production of the new pattern of response.

Full text

PDF
59

Images in this article

56Fig. 1
on p.56

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ANNIS D., HALLENBECK G. A. The effects of partial gastrectomy on canine external pancreatic secretion. Surgery. 1952 Apr;31(4):517–527. [PubMed] [Google Scholar]
  2. BAYLIN G. J., ISLEY J. K., SANDERS A. P., REEVES R. J., RUFFIN J. M., HYMANS J., SHINGLETON W. W. The use of radioactive isotopes in the evaluation of gastrointestinal function. Am J Roentgenol Radium Ther Nucl Med. 1957 Oct;78(4):705–709. [PubMed] [Google Scholar]
  3. KIEKENS R., LUNDH G. Intestinal digestion and absorption after Billroth II gastrectomy; a preliminary report. Acta Chir Scand. 1957 Nov 17;113(5):349–356. [PubMed] [Google Scholar]
  4. MACLEAN L. D., PERRY J. F., KELLY W. D., MOSSER D. G., MANNICK A., WANGENSTEEN O. H. Nutrition following subtotal gastrectomy of four types (Billroth I and II, segmental, and tubular resections). Surgery. 1954 May;35(5):705–718. [PubMed] [Google Scholar]
  5. PFEFFER R. B., STEPHENSON H. E., HINTON J. W. The effect of thoracolumbar sympathectomy and vagus resection on pancreatic function in man. Ann Surg. 1952 Oct;136(4):585–594. [PMC free article] [PubMed] [Google Scholar]
  6. POLAK M., PONTES J. F. The cause of postgastrectomy steatorrhea. Gastroenterology. 1956 Mar;30(3):489–499. [PubMed] [Google Scholar]
  7. RICHMAN A., LESTER L. J., HOLLANDER F., DREILLING D. A., KLEIN A. The effect of subtotal gastrectomy upon external pancreatic secretion in dogs. Gastroenterology. 1954 Feb;26(2):210–220. [PubMed] [Google Scholar]
  8. RUFFIN J. M., KEEVER I. C., CHEARS C., Jr, SHINGLETON W. W., BAYLIN G. J., ISLEY J. K., SANDERS A. P. Further observations on the use of I131-labeled lipids in the study of diseases of the gastrointestinal tract. Gastroenterology. 1958 Mar;34(3):484–490. [PubMed] [Google Scholar]
  9. SHINGLETON W. W., ISLEY J. K., FLOYD R. D., SANDERS A. P., BAYLIN G. J., POSTLETHWAIT R. W., RUFFIN J. M. Studies on postgastrectomy steatorrhea using radioactive triolein and oleic acid. Surgery. 1957 Jul;42(1):12-9; discussion, 19-21. [PubMed] [Google Scholar]
  10. WARREN K. W. Pancreatic considerations in gastric surgery. J Am Med Assoc. 1954 Mar 6;154(10):803–810. doi: 10.1001/jama.1954.02940440001001. [DOI] [PubMed] [Google Scholar]
  11. WELLS C. The late complications of gastrectomy. Ann R Coll Surg Engl. 1955 Mar;16(3):145–162. [PMC free article] [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES