Skip to main content
PMC home page
Gut logoLink to Gut
. 1963 Sep;4(3):193–216. doi: 10.1136/gut.4.3.193

A clinical study of chronic pancreatitis

Oliver Fitzgerald, Patrick Fitzgerald, James Fennelly, Joseph P McMullin, Sylvester J Boland
PMCID: PMC1413444  PMID: 14058261

Abstract

A series of 53 cases of chronic pancreatic disease is described and attention drawn to the frequency with which symptoms are persistent rather than intermittent. A plea is made for the use of the term `progressive' rather than `relapsing' in describing many of these cases. Alcohol was an unimportant factor in the aetiology. The possibility of achieving an accurate and early diagnosis using the serum secretin/pancreozymin test is emphasized. The frequent relief of symptoms and the prevention of progress of the disease by surgery, especially sphincterotomy, is recorded.

Full text

PDF
198

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Archibald E., Gibbons E. C. FURTHER DATA CONCERNING THE EXPERIMENTAL PRODUCTION OF PANCREATITIS. Ann Surg. 1921 Oct;74(4):426–433. doi: 10.1097/00000658-192110000-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BOGOCH A., ROTH J. L., BOCKUS H. L. The effects of morphine on serum amylase and lipase. Gastroenterology. 1954 May;26(5):697–708. [PubMed] [Google Scholar]
  3. BURN C. G. The association of acute pancreatitis with acute coronary thrombosis. Am J Pathol. 1951 Jul-Aug;27(4):680–682. [PubMed] [Google Scholar]
  4. BURTON P., HAMMOND E. M., HARPER A. A., HOWAT H. T., SCOTT J. E., VARLEY H. Serum amylase and serum lipase levels in man after administration of secretin and pancreozymin. Gut. 1960 Jun;1:125–139. doi: 10.1136/gut.1.2.125. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. COMFORT M. W., STEINBERG A. G. Pedigree of a family with hereditary chronic relapsing pancreatitis. Gastroenterology. 1952 May;21(1):54–63. [PubMed] [Google Scholar]
  6. COPE O., CULVER P. J., MIXTER C. G., Jr, NARDI G. L. Pancreatitis, a diagnostic clue to hyperparathyroidism. Ann Surg. 1957 Jun;145(6):857–863. doi: 10.1097/00000658-195706000-00007. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. DOUBILET H., MULHOLLAND J. H. The results of sphincterotomy in pancreatitis. J Mt Sinai Hosp N Y. 1951 Mar-Apr;17(6):458–462. [PubMed] [Google Scholar]
  8. DOUBILET H., POPPEL M. H., MULHOLLAND J. H. Pancreatography; technics, principles, and observations. Radiology. 1955 Mar;64(3):325–339. doi: 10.1148/64.3.325. [DOI] [PubMed] [Google Scholar]
  9. FENNELLY J. J., FITZGERALD O., HEALY J. B. I131 labelled triolein (glyceryltrioleate) and oleic acid131 absorption studies as an index of small intestinal function. Ir J Med Sci. 1959 Oct;NO:462–469. doi: 10.1007/BF02945840. [DOI] [PubMed] [Google Scholar]
  10. FISHER B., FISHER E. R., SELKER R. Further observations on the role of bile in the pathogenesis of pancreatitis. Surg Forum. 1953 Oct;4:406–412. [PubMed] [Google Scholar]
  11. FITZGERALD O., FENNELLY J. J., HINGERTY D. J. Serum studies in man after administration of vitamin A acetate and vitamin A alcohol. I. In normal subjects. Gut. 1961 Sep;2:263–266. doi: 10.1136/gut.2.3.263. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. GAMBILL E. E., BAGGENSTOSS A. H., PRIESTLEY J. T. Chronic relapsing pancreatitis. Fate of fifty-six patients encountered in the years 1939 to 1943, inclusive. Gastroenterology. 1960 Oct;39:404–413. [PubMed] [Google Scholar]
  13. GROSS J. B., COMFORT M. W. Hereditary pancreatitis: report on two additional families. Gastroenterology. 1957 May;32(5):829–854. [PubMed] [Google Scholar]
  14. GROSS J. B., COMFORT M. W., ULRICH J. A. Abnormalities of serum and urinary amino acids in hereditary and non-hereditary pancreatitis. Trans Assoc Am Physicians. 1957;70:127–139. [PubMed] [Google Scholar]
  15. GROSS J. B., HALLENBECK G. A. Chronic relapsing pancreatitis despite achlorhydria. Report of five cases and consideration of pathogenesis. Gastroenterology. 1960 Jun;38:919–925. [PubMed] [Google Scholar]
  16. HEPP J., MOREAUX J. Documents sur les pancréatites avec calcifications. Arch Mal Appar Dig Mal Nutr. 1958 Oct;47(10):1057–1072. [PubMed] [Google Scholar]
  17. HERMANN R. E., DAVIS J. H. The role of incomplete pancreatic duct obstruction in the etiology of pancreatitis. Surgery. 1960 Aug;48:318–329. [PubMed] [Google Scholar]
  18. Harper A. A., Raper H. S. Pancreozymin, a stimulant of the secretion of pancreatic enzymes in extracts of the small intestine. J Physiol. 1943 Jun 30;102(1):115–125. doi: 10.1113/jphysiol.1943.sp004021. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. JOSKE R. A. Aetiological factors in the pancreatitis syndrome. Br Med J. 1955 Dec 17;2(4954):1477–1481. doi: 10.1136/bmj.2.4954.1477. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. KLATSKIN G., GORDON M. Relationship between relapsing pancreatitis and essential hyperlipemia. Am J Med. 1952 Jan;12(1):3–23. doi: 10.1016/0002-9343(52)90164-2. [DOI] [PubMed] [Google Scholar]
  21. LANGMADE C. F., EDMONDSON H. A. Acute pancreatitis during pregnancy and the postpartum period; a report of nine cases. Surg Gynecol Obstet. 1951 Jan;92(1):43–52. [PubMed] [Google Scholar]
  22. MCCOLLUM J. K. Surgical and biochemical aspects of pancreatitis. Br Med J. 1955 Dec 17;2(4954):1482–1484. doi: 10.1136/bmj.2.4954.1482. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. MORRIN F. J., DUNKIN L. Pancreatitis following subtotal gastrectomy. Ir J Med Sci. 1956 Mar;(363):106–114. doi: 10.1007/BF02948470. [DOI] [PubMed] [Google Scholar]
  26. POLLOCK A. V. Acute pancreatitis; analysis of 100 patients. Br Med J. 1959 Jan 3;1(5113):6–14. doi: 10.1136/bmj.1.5113.6. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. POULSEN H. M. Familial lipaemia. A new form of lipoidosis showing increase in neutral fats combined with attacks of acute pancreatitis. Acta Med Scand. 1950;138(6):413–420. [PubMed] [Google Scholar]
  28. RYAN W. A. Chronic relapsing pancreatitis with hypoglycaemia. J Ir Med Assoc. 1957 Dec;41(246):187–190. [PubMed] [Google Scholar]
  29. SUN D. C., SHAY H. Pancreozymin-secretin test. The combined study of serum enzymes and duodenal contents in the diagnosis of pancreatic disease. Gastroenterology. 1960 Apr;38:570–581. [PubMed] [Google Scholar]
  30. WARREN K. W., CATTELL R. B. Pancreatic surgery. N Engl J Med. 1959 Aug 6;261(6):280–contd. doi: 10.1056/NEJM195908062610606. [DOI] [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES