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. 1963 Sep;4(3):292–298. doi: 10.1136/gut.4.3.292

Acute folic acid deficiency of unknown aetiology: temperate sprue

W T Cooke, D J Fone, E V Cox, M J Meynell, R Gaddie
PMCID: PMC1413449  PMID: 14058271

Abstract

The 20 patients described could be included in the group of patients diagnosed as `idiopathic steatorrhoea'. However, their histories were short and diarrhoea was not a major feature. Since megaloblastic anaemia due to folic acid deficiency was a common feature it is suggested that these patients may form a homogeneous group and the diagnostic label of temperate sprue is suggested.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ANDERSON B., BELCHER E. H., CHANARIN I., MOLLIN D. L. The urinary and faecal excretion of radioactivity after oral doses of H3-folic acid. Br J Haematol. 1960 Oct;6:439–455. doi: 10.1111/j.1365-2141.1960.tb06262.x. [DOI] [PubMed] [Google Scholar]
  2. COOKE W. T. Adult coeliac disease and other disorders associated with steatorrhoea. Br Med J. 1958 Aug 2;2(5091):261–265. doi: 10.1136/bmj.2.5091.261. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. COOKE W. T., FONE D. J., COX E. V., MEYNELL M. J., GADDIE R. ADULT COELIAC DISEASE. Gut. 1963 Sep;4:279–291. doi: 10.1136/gut.4.3.279. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. COOKE W. T., PEENEY A. L. P., HAWKINS C. F. Symptoms, signs and diagnostic features of idiopathic steatorrhoea. Q J Med. 1953 Jan;22(85):59–78. [PubMed] [Google Scholar]
  5. FONE D. J., MEYNELL M. J., HARRIS E. L., COOKE W. T., BREWER D. B., COX E. V. Jejunal biopsy in adult coeliac disease and allied disorders. Lancet. 1960 Apr 30;1(7131):933–939. doi: 10.1016/s0140-6736(60)90832-1. [DOI] [PubMed] [Google Scholar]
  6. JOHNSON S., SWAMINATHAN S. P., BAKER S. J. Changes in serum vitamin B12 levels in patients with megaloblastic anaemia treated with folic acid. J Clin Pathol. 1962 May;15:274–277. doi: 10.1136/jcp.15.3.274. [DOI] [PMC free article] [PubMed] [Google Scholar]

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