Skip to main content
Gut logoLink to Gut
. 1981 May;22(5):388–392. doi: 10.1136/gut.22.5.388

Aetiology of acute diarrhoea in adults.

J Jewkes, H E Larson, A B Price, P J Sanderson, H A Davies
PMCID: PMC1419238  PMID: 7250751

Abstract

We have studied 73 adults with acute diarrhoea and identified a micro-organism or toxin likely to be the cause in 58%. In addition to routinely cultured bacteria, Campylobacter coli/jejuni and Clostridium difficile were important pathogens in the community. Patients who developed diarrhoea after antibiotic use had a distinctive clinical syndrome and comprised the third largest group of cases. Clinical, epidemiological, and histological features in an additional group with negative cultures and no antibiotic history suggest that an additional bacterial pathogen remains to be identified as a cause of acute diarrhoea in adults.

Full text

PDF
388

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brunton W. A., Heggie D. Campylobacter-associated diarrhoea in Edinburgh. Br Med J. 1977 Oct 8;2(6092):956–956. doi: 10.1136/bmj.2.6092.956. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Day D. W., Mandal B. K., Morson B. C. The rectal biopsy appearances in Salmonella colitis. Histopathology. 1978 Mar;2(2):117–131. doi: 10.1111/j.1365-2559.1978.tb01700.x. [DOI] [PubMed] [Google Scholar]
  3. Dickinson R. J., Gilmour H. M., McClelland D. B. Rectal biopsy in patients presenting to an infectious disease unit with diarrhoeal disease. Gut. 1979 Feb;20(2):141–148. doi: 10.1136/gut.20.2.141. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Dolin R., Blacklow N. R., DuPont H., Formal S., Buscho R. F., Kasel J. A., Chames R. P., Hornick R., Chanock R. M. Transmission of acute infectious nonbacterial gastroenteritis to volunteers by oral administration of stool filtrates. J Infect Dis. 1971 Mar;123(3):307–312. doi: 10.1093/infdis/123.3.307. [DOI] [PubMed] [Google Scholar]
  5. Gross R. J., Scotland S. M., Rowe B. Enterotoxigenic Escherichia coli causing diarrhoea in travellers returning to the United Kingdom. Br Med J. 1979 Jun 2;1(6176):1463–1463. doi: 10.1136/bmj.1.6176.1463. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Lewis H. M., Parry J. V., Davies H. A., Parry R. P., Mott A., Dourmashkin R. R., Sanderson P. J., Tyrrell D. A., Valman H. B. A year's experience of the rotavirus syndrome and its association with respiratory illness. Arch Dis Child. 1979 May;54(5):339–346. doi: 10.1136/adc.54.5.339. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Pai C. H., Sorger S., Lackman L., Sinai R. E., Marks M. I. Campylobacter gastroenteritis in children. J Pediatr. 1979 Apr;94(4):589–591. doi: 10.1016/s0022-3476(79)80016-5. [DOI] [PubMed] [Google Scholar]
  8. Pearson A. D., Suckling W. G., Ricciardi I. D., Knill M., Ware E. Campylobacter-associated diarrhoea in Southampton. Br Med J. 1977 Oct 8;2(6092):955–956. doi: 10.1136/bmj.2.6092.955-b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Price A. B., Davies D. R. Pseudomembranous colitis. J Clin Pathol. 1977 Jan;30(1):1–12. doi: 10.1136/jcp.30.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Price A. B., Jewkes J., Sanderson P. J. Acute diarrhoea: Campylobacter colitis and the role of rectal biopsy. J Clin Pathol. 1979 Oct;32(10):990–997. doi: 10.1136/jcp.32.10.990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Rowland M. G., Davies H., Patterson S., Dourmashkin R. R., Tyrrell D. A., Matthews T. H., Parry J., Hall J., Larson H. E. Viruses and diarrhoea in West Africa and London: A collaborative study. Trans R Soc Trop Med Hyg. 1978;72(1):95–98. doi: 10.1016/0035-9203(78)90308-5. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Sakurai Y., Tsuchiya H., Ikegami F., Funatomi T., Takasu S., Uchikoshi T. Acute right-sided hemorrhagic colitis associated with oral administration of ampicillin. Dig Dis Sci. 1979 Dec;24(12):910–915. doi: 10.1007/BF01311944. [DOI] [PubMed] [Google Scholar]
  13. Skirrow M. B. Campylobacter enteritis: a "new" disease. Br Med J. 1977 Jul 2;2(6078):9–11. doi: 10.1136/bmj.2.6078.9. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Toffler R. B., Pingoud E. G., Burrell M. I. Acute colitis related to penicillin and penicillin derivatives. Lancet. 1978 Sep 30;2(8092 Pt 1):707–709. doi: 10.1016/s0140-6736(78)92704-6. [DOI] [PubMed] [Google Scholar]
  15. Wadström T., Aust-Kettis A., Habte D., Holmgren J., Meeuwisse G., Möllby R., Söderlind O. Enterotoxin-producing bacteria and parasites in stools of Ethiopian children with diarrhoeal disease. Arch Dis Child. 1976 Nov;51(11):865–870. doi: 10.1136/adc.51.11.865. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES