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. 1982 Mar;23(3):198–201. doi: 10.1136/gut.23.3.198

Crohn's disease of the mouth: an indicator of intestinal involvement.

C Scully, K M Cochran, R I Russell, M M Ferguson, M A Ghouri, F D Lee, D G MacDonald, P B McIntyre
PMCID: PMC1419642  PMID: 7068045

Abstract

Nineteen patients with clinical evidence of oral Crohn's disease but no intestinal symptoms were studied. Oral lesions in all patients were shown histologically to have lymphoedema with or without chronic granulomas consistent with Crohn's disease. Seven patients (37%) had demonstrable intestinal disease on rectal biopsy and four of these had abnormal bowel radiology. All seven had evidence of nutritional deficiency. Patients with clinical features suggesting oral Crohn's disease may have evidence of Crohn's disease in the intestine, although this may not be clinically apparent.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Asquith P., Thompson R. A., Cooke W. T. Oral manifestations of Crohn's disease. Gut. 1975 Apr;16(4):249–254. doi: 10.1136/gut.16.4.249. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BAZEX A., DUPRE A. Les infiltrations lymphoedèmateuses, sarcoidiques et adenomateuses chroniques du visage: syndrome de Melkersson-Rosenthal, fibroedème de Stevens, syndrome d'Ascher. Toulouse Med. 1957 Feb;58(2):89–109. [PubMed] [Google Scholar]
  3. Baker W. N., Milton-Thompson G. J. The anal lesion as the sole presenting symptom of intestinal Crohn's disease. Gut. 1971 Oct;12(10):865–865. [PubMed] [Google Scholar]
  4. Bernstein M. L., McDonald J. S. Oral lesions in Crohn's disease: report of two cases and update of the literature. Oral Surg Oral Med Oral Pathol. 1978 Aug;46(2):234–245. doi: 10.1016/0030-4220(78)90198-6. [DOI] [PubMed] [Google Scholar]
  5. Carr D. Granulomatous cheilitis in Crohn's disease. Br Med J. 1974 Dec 14;4(5945):636–636. doi: 10.1136/bmj.4.5945.636. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Croft C. B., Wilkinson A. R. Ulceration of the mouth, pharynx, and larynx in Crohn's disease of the intestine. Br J Surg. 1972 Apr;59(4):249–252. doi: 10.1002/bjs.1800590402. [DOI] [PubMed] [Google Scholar]
  7. DAHM G., SCH0NKO H. [On the genesis of cheilitis granulomatosa, respectively Melkersson-Rosenthal syndrome]. Arch Klin Exp Dermatol. 1961;212:616–637. doi: 10.1007/BF00475888. [DOI] [PubMed] [Google Scholar]
  8. Dudeney T. P. Crohn's disease of the mouth. Proc R Soc Med. 1969 Dec 12;62(12):1237–1237. [PMC free article] [PubMed] [Google Scholar]
  9. Greenstein A. J., Janowitz H. D., Sachar D. B. The extra-intestinal complications of Crohn's disease and ulcerative colitis: a study of 700 patients. Medicine (Baltimore) 1976 Sep;55(5):401–412. doi: 10.1097/00005792-197609000-00004. [DOI] [PubMed] [Google Scholar]
  10. Taylor V. E., Smith C. J. Oral manifestations of Crohn's disease without demonstrable gastrointestinal lesions. Oral Surg Oral Med Oral Pathol. 1975 Jan;39(1):58–66. doi: 10.1016/0030-4220(75)90396-5. [DOI] [PubMed] [Google Scholar]
  11. Tyldesley W. R. Oral Crohn's disease and related conditions. Br J Oral Surg. 1979 Jul;17(1):1–9. doi: 10.1016/0007-117x(79)90001-5. [DOI] [PubMed] [Google Scholar]
  12. Töndury G. D. Cheilitis granulomatosa und Morbus Crohn. Schweiz Rundsch Med Prax. 1977 Jun 28;66(26):792–793. [PubMed] [Google Scholar]
  13. Varley E. W. Crohn's disease of the mouth. Report of three cases. Oral Surg Oral Med Oral Pathol. 1972 Apr;33(4):570–578. doi: 10.1016/0030-4220(72)90369-6. [DOI] [PubMed] [Google Scholar]

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