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. 1982 Mar;23(3):243–246. doi: 10.1136/gut.23.3.243

Isolated co-lipase deficiency in two brothers.

H Hildebrand, B Borgström, A Békássy, C Erlanson-Albertsson, I Helin
PMCID: PMC1419644  PMID: 7068048

Abstract

Two normally developed Assyrian brothers with isolated pancreatic co-lipase deficiency are described. They presented at the age of 5-6 years with loose stools. They had steatorrhoea, and analysis of exocrine pancreatic enzymes in the small intestine showed co-lipase deficiency, while amylase, chymotrypsin, trypsin and lipase were normal. Intraduodenal infusion of purified co-lipase improved fat digestion measured by the triolein breath test. Their steatorrhoea diminished on treatment with enteric-coated pancreatic enzymes.

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Selected References

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