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. 1992 Dec;77(4):515–519.

The distribution of immunoreactive interferon-gamma-containing cells in normal human tissues.

F Brett 1, A Mowat 1, M A Farquharson 1, M McGill 1, C Hind 1, J Richmond 1, D Murray 1, N U Khan 1, A K Foulis 1
PMCID: PMC1421654  PMID: 1493923

Abstract

An immunohistochemical technique has been used to study the distribution of lymphocytes expressing interferon-gamma in normal adult tissues. The greatest concentrations of these cells were seen in mucosal sites exposed to a resident microflora. It is proposed that such organisms, by eliciting immune responses, provide the stimulus for the production of 'physiological' interferon-gamma. This in turn may act to preserve the 'tone' or readiness of the immune system.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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