Abstract
1 The methodology used in studies to assess the effects of drugs on car-driving performance is reviewed.
2 Clobazam 20 mg, diazepam 10 mg or placebo were administered daily for 3 d to 24 male students with a high neuroticism score (on the Cattell Personality Factors Questionnaire).
3 Car-driving performance was assessed on the second day in real traffic conditions; tests of attention and concentration and subjective assessments were made on the third day.
4 Diazepam 10 mg significantly impaired braking reaction time in comparison with clobazam 20 mg and placebo (P < 0.01). Subjects also reported feeling more `depressed' and lethargic after diazepam.
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Selected References
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