Abstract
1 Red cell methaemoglobin levels were found to be significantly raised in healthy subjects given a 14-day course of primaquine with chloroquine on the first 3 days. 2 The methaemoglobin levels were not related to the quantity of primaquine excreted. 3 No primaquine could be detected in the plasma at 24 h following the last three daily doses.
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- CLAYMAN C. B., ARNOLD J., HOCKWALD R. S., YOUNT E. H., Jr, EDGCOMB J. H., ALVING A. S. Toxicity of primaquine in Caucasians. J Am Med Assoc. 1952 Aug 23;149(17):1563–1568. doi: 10.1001/jama.1952.72930340022010b. [DOI] [PubMed] [Google Scholar]
- COWAN W. K., EVANS D. A. PRIMAQUINE AND METHEMOGLOBIN. Clin Pharmacol Ther. 1964 May-Jun;5:307–309. doi: 10.1002/cpt196453307. [DOI] [PubMed] [Google Scholar]
- Greaves J., Price-Evans D. A., Gilles H. M., Baty J. D. A selected ion monitoring assay for primaquine in plasma and urine. Biomed Mass Spectrom. 1979 Mar;6(3):109–112. doi: 10.1002/bms.1200060306. [DOI] [PubMed] [Google Scholar]
- JONES R., Jr, JACKSON L. S., DI LORENZO A., MARX R. L., LEVY B. L., KENNY E. C., GILBERT M., JOHNSTON M. N., ALVING A. S. Korean vivax malaria. III. Curative effect and toxicity of primaquine in doses from 10 to 30 mg. daily. Am J Trop Med Hyg. 1953 Nov;2(6):977–982. [PubMed] [Google Scholar]