Abstract
A case of Wegener's granulomatosis is described, in which the presentation was blood stained mucus diarrhoea. Severe ileal, caecal, and rectal involvement improved rapidly after treatment with cyclophosphamide, azathioprine, and prednisolone. Although intestinal disease is an uncommon feature of Wegener's granulomatosis, both in our own experience (four of 45 cases) and in the literature, this diagnosis should be considered in view of the response to appropriate therapy.
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- Brandwein S., Esdaile J., Danoff D., Tannenbaum H. Wegener's granulomatosis. Clinical features and outcome in 13 patients. Arch Intern Med. 1983 Mar;143(3):476–479. doi: 10.1001/archinte.143.3.476. [DOI] [PubMed] [Google Scholar]
- Camilleri M., Pusey C. D., Chadwick V. S., Rees A. J. Gastrointestinal manifestations of systemic vasculitis. Q J Med. 1983 Spring;52(206):141–149. [PubMed] [Google Scholar]
- Carrington C. B., Liebow A. Limited forms of angiitis and granulomatosis of Wegener's type. Am J Med. 1966 Oct;41(4):497–527. doi: 10.1016/0002-9343(66)90214-2. [DOI] [PubMed] [Google Scholar]
- FAHEY J. L., LEONARD E., CHURG J., GODMAN G. Wegener's granulomatosis. Am J Med. 1954 Aug;17(2):168–179. doi: 10.1016/0002-9343(54)90255-7. [DOI] [PubMed] [Google Scholar]
- Fauci A. S., Haynes B. F., Katz P., Wolff S. M. Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. Ann Intern Med. 1983 Jan;98(1):76–85. doi: 10.7326/0003-4819-98-1-76. [DOI] [PubMed] [Google Scholar]
- Fauci A. S., Wolff S. M. Wegener's granulomatosis: studies in eighteen patients and a review of the literature. Medicine (Baltimore) 1973 Nov;52(6):535–561. doi: 10.1097/00005792-197311000-00002. [DOI] [PubMed] [Google Scholar]
- GODMAN G. C., CHURG J. Wegener's granulomatosis: pathology and review of the literature. AMA Arch Pathol. 1954 Dec;58(6):533–553. [PubMed] [Google Scholar]
- Illum P., Thorling K. Wegener's granulomatosis. Long-term results of treatment. Ann Otol Rhinol Laryngol. 1981 May-Jun;90(3 Pt 1):231–235. doi: 10.1177/000348948109000307. [DOI] [PubMed] [Google Scholar]
- McNabb W. R., Lennox M. S., Wedzicha J. A. Small intestinal perforation in Wegener's granulomatosis. Postgrad Med J. 1982 Feb;58(676):123–125. doi: 10.1136/pgmj.58.676.123. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WALTON E. W. Giant-cell granuloma of the respiratory tract (Wegener's granulomatosis). Br Med J. 1958 Aug 2;2(5091):265–270. doi: 10.1136/bmj.2.5091.265. [DOI] [PMC free article] [PubMed] [Google Scholar]