Abstract
The subsequent progress of 152 patients treated medically in the Nottingham hospitals for bleeding gastric ulceration was analysed four to eight years later by the use of life tables. The overall cumulative rate of ulcer haemorrhage, perforation or related death was found to be 19%. Women had a greater rate than men (women 21%, men 14%) but this difference was not statistically significant. The risk of developing a recurrent complication fell with time in both groups. Women were older than men at the time of their index admission and women who suffered a late complication were significantly older than those remaining well at the end of the follow up period. No similar differences existed for men. The risk of having a late complication from a bleeding gastric ulcer compares favourably with that reported under similar circumstances for duodenal ulceration. Attempts to reduce the late complication rate should concentrate on those patients shown to be at a greater risk - that is, elderly women.
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Selected References
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- ARIAS I. M., ZAMCHECK N., THROWER W. B. Recurrence of hemorrhage from medically treated gastric ulcers; four-to eight-year follow-up of forty-seven patients. AMA Arch Intern Med. 1958 Feb;101(2):369–376. doi: 10.1001/archinte.1958.00260140201030. [DOI] [PubMed] [Google Scholar]
- BADGER G. F., BEAMS A. J., CHINN A. B., LITTELL A. S. Acute hemorrhage from peptic ulcer; a follow-up study of 310 patients. N Engl J Med. 1956 Nov 22;255(21):973–978. doi: 10.1056/NEJM195611222552101. [DOI] [PubMed] [Google Scholar]
- Borland J. L., Sr, Hancock W. R., Borland J. L., Jr Recurrent upper gastrointestinal hemorrhage in peptic ulcer. Gastroenterology. 1967 Apr;52(4):631–637. [PubMed] [Google Scholar]
- Coldman A. J., Elwood J. M. Examining survival data. Can Med Assoc J. 1979 Oct 20;121(8):1065-8, 1071. [PMC free article] [PubMed] [Google Scholar]
- Dronfield M. W., Langman M. J., Atkinson M., Balfour T. W., Bell G. D., Vellacott K. D., Amar S. S., Knapp D. R. Outcome of endoscopy and barium radiography for acute upper gastrointestinal bleeding: controlled trial in 1037 patients. Br Med J (Clin Res Ed) 1982 Feb 20;284(6315):545–548. doi: 10.1136/bmj.284.6315.545. [DOI] [PMC free article] [PubMed] [Google Scholar]
- FLOOD C. A., HENNIG G. C. Recurrence in gastric ulcer under medical management. Gastroenterology. 1950 Sep;16(1):57–72. [PubMed] [Google Scholar]
- GRACE W. J., MITTY W. F. Does subtotal gastrectomy in bleeding peptic ulcer prevent recurrence of bleeding? Am J Dig Dis. 1962 Jan;7:69–74. doi: 10.1007/BF02231932. [DOI] [PubMed] [Google Scholar]
- Harvey R. F., Langman M. J. The late results of medical and surgical treatment for bleeding duodenal ulcer. Q J Med. 1970 Oct;39(156):539–547. [PubMed] [Google Scholar]
- LEAPE L. L., WELCH C. E. LATE PROGNOSIS OF PATIENTS WITH UPPER GASTROINTESTINAL HEMORRHAGE. Am J Surg. 1964 Feb;107:297–305. doi: 10.1016/0002-9610(64)90271-5. [DOI] [PubMed] [Google Scholar]
- SWYNNERTON B. F., TANNER N. C. Chronic gastric ulcer; a comparison between a gastroscopically controlled series treated medically and a series treated by surgery. Br Med J. 1953 Oct 17;2(4841):841–847. doi: 10.1136/bmj.2.4841.841. [DOI] [PMC free article] [PubMed] [Google Scholar]