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. 1988 Nov;29(11):1595–1602. doi: 10.1136/gut.29.11.1595

Family occurrence of achalasia and diffuse spasm of the oesophagus.

T Frieling 1, W Berges 1, F Borchard 1, H J Lübke 1, P Enck 1, M Wienbeck 1
PMCID: PMC1433819  PMID: 3061886

Abstract

In view of the unknown aetiology of achalasia and diffuse oesophageal spasm we report four families (father/son, mother/son, brother/brother, cousin/cousin) with achalasia and oesophageal spasm examined by radiology, endoscopy and manometry. Family occurrence of oesophageal motor disorders supports the hypothesis that a genetic trait may play a role in the pathogenesis. The family coincidence of achalasia and oesophageal spasm supports a close relationship between the two diseases.

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Selected References

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