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. 1985 Apr;47(4):491–496. doi: 10.1016/S0006-3495(85)83942-4

Intracellular gas supersaturation tolerances of erythrocytes and resealed ghosts.

B B Hemmingsen, N A Steinberg, E A Hemmingsen
PMCID: PMC1435121  PMID: 3921076

Abstract

Intact mammalian, avian, and amphibian erythrocytes were saturated with up to 300 atm nitrogen or argon gas and rapidly decompressed. Despite the profuse nucleation of gas bubbles in the suspending fluid, no evidence of intracellular gas bubble nucleation was found; all or most of the cells remained intact and little or no hemoglobin escaped. Internal bubbles were similarly absent from resealed ghosts of human erythrocytes as shown by lack of disintegration and by retention of an entrapped fluorescent compound. The absence of bubbles may indicate that much of the internal water does not have the same nucleation properties as external water.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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