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. 1977 May;32(5):681–687.

Reactivity and crossreactivity of mouse helper T cells to malaria parasites.

J H Playfair, J B De Souza, B J Cottrell
PMCID: PMC1445333  PMID: 324898

Abstract

The mouse helper T-cell response to four plasmodial and babesial parasites was measured by using them as carriers for a standard hapten (TNP). Helper T cells appeared to recognize all the parasites, but not to be able to distinguish between them. Helper T-cell responses could be augmented by vaccination with formalin-fixed parasites. However vaccination did not always confer protection against infection. Conversely, mice resistant to infection because of prior recovery from a homologous or heterologous infection had normal or reduced helper T-cell responses. It is concluded that resistance to infection with these parasites, though dependent on T cells, may not only involve the helper T-cell subpopulation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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