Skip to main content
PMC home page
Immunology logoLink to Immunology
. 1977 Oct;33(4):501–505.

IgE in experiemental schistosomiasis. I. Serum IgE levels after infection by Schistosoma mansoni in various strains of rats.

R Rousseaux-Prevost, H Bazin, A Capron
PMCID: PMC1445395  PMID: 924519

Abstract

Serum IgE levels were measured by radioimmunoassay in four strains of rats, before and after infection by Schistosoma mansoni. Differences were observed in basal IgE levels, depending on the strain considered. Serum IgE rose 10--20 days after infection and the maximum level, between days 30 and 50, ranged from 14 to 60 times the basal level. One of the most characteristic features of IgE production in rat schistosomiasis was the persistence of high IgE levels for a long time after rejection of the worms.

Full text

PDF
505

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bazin H., Querinjean P., Beckers A., Heremans J. F., Dessy F. Transplantable immunoglobulin-secreting tumours in rats. IV. Sixty-three IgE-secreting immunocytoma tumours. Immunology. 1974 Apr;26(4):713–723. [PMC free article] [PubMed] [Google Scholar]
  2. Bennich H., Johansson S. G. Structure and function of human immunoglobulin E. Adv Immunol. 1971;13:1–55. doi: 10.1016/s0065-2776(08)60182-0. [DOI] [PubMed] [Google Scholar]
  3. Capron A., Dessaint J. P., Capron M., Bazin H. Specific IgE antibodies in immune adherence of normal macrophages to Schistosoma mansoni schistosomules. Nature. 1975 Feb 6;253(5491):474–475. doi: 10.1038/253474a0. [DOI] [PubMed] [Google Scholar]
  4. Carson D., Metzger H., Bazin H. Simple radio-immunoassay for the measurement of human and rat IgE levels by ammonium sulfate precipitation. J Immunol. 1975 Aug;115(2):561–563. [PubMed] [Google Scholar]
  5. Carson D., Metzger H., Bloch K. J. Serum IgE levels during the potentiated reagin response to egg albumin in rats infected with Nippostrongylus brasiliensis. J Immunol. 1975 Jan;114(1 Pt 2):521–523. [PubMed] [Google Scholar]
  6. Dessaint J. P., Bout D., Wattre P., Capron A. Quantitative determination of specific IgE antibodies to Echinococcus granulosus and IgE levels in sera from patients with hydatid disease. Immunology. 1975 Nov;29(5):813–823. [PMC free article] [PubMed] [Google Scholar]
  7. Gleich G. J., Averbeck A. K., Swedlund H. A. Measurement of IgE in normal and allergic serum by radioimmunoassay. J Lab Clin Med. 1971 Apr;77(4):690–698. [PubMed] [Google Scholar]
  8. Hogarth-Scott R. S., Johansson S. G., Bennich H. Antibodies to Toxocara in the sera of visceral larva migrans patients: the significance of raised levels of IgE. Clin Exp Immunol. 1969 Dec;5(6):619–625. [PMC free article] [PubMed] [Google Scholar]
  9. Ishizaka T., Urban J. F., Jr, Ishizaka K. IgE formation in the rat following infection with Nippostrongylus brasiliensis. I. Proliferation and differentiation of IgE-bearing cells. Cell Immunol. 1976 Mar 15;22(2):248–261. doi: 10.1016/0008-8749(76)90027-7. [DOI] [PubMed] [Google Scholar]
  10. Jarrett E. E., Haig D. M. Time course studies on rat IgE production in N. Brasiliensis infection. Clin Exp Immunol. 1976 May;24(2):346–351. [PMC free article] [PubMed] [Google Scholar]
  11. Jarrett E., Bazin H. Elevation of total serum IgE in rats following helminth parasite infection. Nature. 1974 Oct 18;251(5476):613–614. doi: 10.1038/251613a0. [DOI] [PubMed] [Google Scholar]
  12. McConahey P. J., Dixon F. J. A method of trace iodination of proteins for immunologic studies. Int Arch Allergy Appl Immunol. 1966;29(2):185–189. doi: 10.1159/000229699. [DOI] [PubMed] [Google Scholar]
  13. Ogilvie B. M., Smithers S. R., Terry R. J. Reagin-like antibodies in experimental infections of Schistosoma mansoni and the passive transfer of resistance. Nature. 1966 Mar 19;209(5029):1221–1223. doi: 10.1038/2091221a0. [DOI] [PubMed] [Google Scholar]
  14. Orr T. S., Blair A. M. Potentiated reagin response to egg albumin and conalbumin in Nippostrongylus brasiliensis infected rats. Life Sci. 1969 Oct 15;8(20):1073–1077. doi: 10.1016/0024-3205(69)90459-7. [DOI] [PubMed] [Google Scholar]
  17. Rowe D. S. Radioactive single radial diffusion: a method for increasing the sensitivity of immunochemical quantification of proteins in agar gel. Bull World Health Organ. 1969 Apr;40(4):613–616. [PMC free article] [PubMed] [Google Scholar]
  18. Sadun E. H., Gore R. W. Schistosoma mansoni and S. haematobium: homocytotropic reagin-like antibodies in infections of man and experimental animals. Exp Parasitol. 1970 Dec;28(3):435–449. doi: 10.1016/0014-4894(70)90112-8. [DOI] [PubMed] [Google Scholar]
  19. Smithers S. R., Terry R. J. The infection of laboratory hosts with cercariae of Schistosoma mansoni and the recovery of the adult worms. Parasitology. 1965 Nov;55(4):695–700. doi: 10.1017/s0031182000086248. [DOI] [PubMed] [Google Scholar]
  20. Urquhart G. M., Mulligan W., Eadie R. M., Jennings F. W. Immunological studies on Nippostrongylus brasiliensis infection in the rat: the role of local anaphylaxis. Exp Parasitol. 1965 Oct;17(2):210–217. doi: 10.1016/0014-4894(65)90023-8. [DOI] [PubMed] [Google Scholar]

Articles from Immunology are provided here courtesy of British Society for Immunology

RESOURCES