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. 1988 Mar;63(3):363–367.

Vaccines to protect Hereford cattle against the cattle tick, Boophilus microplus.

J P Opdebeeck 1, J Y Wong 1, L A Jackson 1, C Dobson 1
PMCID: PMC1454765  PMID: 3350577

Abstract

Vaccines made from gut and gut and synganglion tissue dissected from Boophilus microplus gave 87% and 80% protection, respectively, compared with adjuvant-injected controls in cattle against three infestations with 20,000 larval ticks administered over 14 days. A vaccine prepared from synganglion alone did not protect cattle. Ticks collected from vaccinated cattle produced 95% and 91% fewer eggs, respectively, than ticks from control animals. Vaccinated cattle were protected (36%) 7 months after they had been immunized with tick antigens. Antibody responses to the vaccines were detected by enzyme-linked immunosorbent assay (ELISA).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ackerman S., Clare F. B., McGill T. W., Sonenshine D. E. Passage of host serum components, including antibody, across the digestive tract of Dermacentor variabilis (Say). J Parasitol. 1981 Oct;67(5):737–740. [PubMed] [Google Scholar]
  2. Agbede R. I., Kemp D. H. Immunization of cattle against Boophilus microplus using extracts derived from adult female ticks: histopathology of ticks feeding on vaccinated cattle. Int J Parasitol. 1986 Feb;16(1):35–41. doi: 10.1016/0020-7519(86)90062-7. [DOI] [PubMed] [Google Scholar]
  3. Alger N. E., Cabrera E. J. An increase in death rate of Anopheles stephensi fed on rabbits immunized with mosquito antigen. J Econ Entomol. 1972 Feb;65(1):165–168. doi: 10.1093/jee/65.1.165. [DOI] [PubMed] [Google Scholar]
  4. Allen J. R., Humphreys S. J. Immunisation of guinea pigs and cattle against ticks. Nature. 1979 Aug 9;280(5722):491–493. doi: 10.1038/280491a0. [DOI] [PubMed] [Google Scholar]
  5. Brossard M., Rais O. Passage of hemolysins through the midgut epithelium of female Ixodes ricinus L. fed on rabbits infested or reinfested with ticks. Experientia. 1984 Jun 15;40(6):561–563. doi: 10.1007/BF01982330. [DOI] [PubMed] [Google Scholar]
  6. Fujisaki K., Kamio T., Kitaoka S. Passage of host serum components, including antibodies specific for Theileria sergenti, across the digestive tract of argasid and ixodid ticks. Ann Trop Med Parasitol. 1984 Aug;78(4):449–450. doi: 10.1080/00034983.1984.11811847. [DOI] [PubMed] [Google Scholar]
  7. Johnston L. A., Kemp D. H., Pearson R. D. Immunization of cattle against Boophilus microplus using extracts derived from adult female ticks: effects of induced immunity on tick populations. Int J Parasitol. 1986 Feb;16(1):27–34. doi: 10.1016/0020-7519(86)90061-5. [DOI] [PubMed] [Google Scholar]
  8. Kemp D. H., Agbede R. I., Johnston L. A., Gough J. M. Immunization of cattle against Boophilus microplus using extracts derived from adult female ticks: feeding and survival of the parasite on vaccinated cattle. Int J Parasitol. 1986 Apr;16(2):115–120. doi: 10.1016/0020-7519(86)90096-2. [DOI] [PubMed] [Google Scholar]
  9. Markwell M. A., Haas S. M., Bieber L. L., Tolbert N. E. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal Biochem. 1978 Jun 15;87(1):206–210. doi: 10.1016/0003-2697(78)90586-9. [DOI] [PubMed] [Google Scholar]
  10. Opdebeeck J., Norcross N. L. Enzyme immunoassay for detection of antibodies specific for staphylococcal alpha haemolysin in bovine milk. Res Vet Sci. 1981 Jan;30(1):83–86. [PubMed] [Google Scholar]
  11. Roberts J. A., Kerr J. D. Boophilus microplus: passive transfer of resistance in cattle. J Parasitol. 1976 Jun;62(3):485–488. [PubMed] [Google Scholar]
  12. Stewart N. P., Callow L. L., Duncalfe F. Biological comparisons between a laboratory-maintained and a recently isolated field strain of Boophilus microplus. J Parasitol. 1982 Aug;68(4):691–694. [PubMed] [Google Scholar]
  13. Wikel S. K., Allen J. R. Acquired resistance to ticks. III. Cobra venom factor and the resistance response. Immunology. 1978 Apr;32(4):457–465. [PMC free article] [PubMed] [Google Scholar]
  14. Wikel S. K. The induction of host resistance to tick infestation with a salivary gland antigen. Am J Trop Med Hyg. 1981 Jan;30(1):284–288. doi: 10.4269/ajtmh.1981.30.284. [DOI] [PubMed] [Google Scholar]

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