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. 1970 Nov;19(5):729–734.

Antigens in pigeon breeders' disease

J H Edwards, J J Barboriak, J N Fink
PMCID: PMC1455654  PMID: 4098599

Abstract

It has been shown that many pigeon materials contain one or more of four pigeon proteins—pigeon γ-globulin (PGG), pigeon serum albumin (PSA), pigeon β-globulin (PBG) and a protein cross-reacting immunologically with PGG termed XPGG. It is thought that the ability of seemingly unrelated sources of pigeon material, e.g. pigeon droppings, serum, egg yolk and white to react with sera from cases of pigeon breeders' disease is due to the presence of PGG, PSA, PBG or XPGG in these materials.

Only in pigeon droppings were important antigens other than PGG, PSA, PBG and XPGG found and it is possible that pigeon droppings are the only `complete' source of antigens concerned with the disease unless specified conditions arise.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BARBORIAK J. J., SOSMAN A. J., REED C. E. SEROLOGICAL STUDIES IN PIGEON BREEDER'S DISEASE. J Lab Clin Med. 1965 Apr;65:600–604. [PubMed] [Google Scholar]
  2. Barboriak J. J., Fink J. N., Scribner G. H. Antigenic specificity in a hypersensitivity pneumonitis. Int Arch Allergy Appl Immunol. 1968;33(5):473–477. doi: 10.1159/000230062. [DOI] [PubMed] [Google Scholar]
  3. Edwards J. H., Fink J. N., Barboriak J. J. Excretion of pigeon serum proteins in pigeon droppings. Proc Soc Exp Biol Med. 1969 Dec;132(3):907–911. doi: 10.3181/00379727-132-34334. [DOI] [PubMed] [Google Scholar]
  4. FRANK R. C. Farmer's lung; a form of pneumoconiosis due to organic dusts. Am J Roentgenol Radium Ther Nucl Med. 1958 Feb;79(2):189–215. [PubMed] [Google Scholar]
  5. Fink J. N., Barboriak J. J., Sosman A. J. Immunologic studies of pigeon breeder's disease. J Allergy. 1967 Apr;39(4):214–221. doi: 10.1016/0021-8707(67)90013-5. [DOI] [PubMed] [Google Scholar]
  6. Fink J. N., Sosman A. J., Barboriak J. J., Schlueter D. P., Holmes R. A. Pigeon breeders' disease. A clinical study of a hypersensitivity pneumonitis. Ann Intern Med. 1968 Jun;68(6):1205–1219. doi: 10.7326/0003-4819-68-6-1205. [DOI] [PubMed] [Google Scholar]
  7. Fink J. N., Tebo T., Barboriak J. J. Differences in the immune responses of pigeon breeders to pigeon serum proteins. J Lab Clin Med. 1969 Aug;74(2):325–330. [PubMed] [Google Scholar]
  8. Martin N. H. The immunoglobulins: a review. J Clin Pathol. 1969 Mar;22(2):117–131. doi: 10.1136/jcp.22.2.117. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. OSSERMAN E. F. A modified technique of immunoelectrophoresis facilitating the identification of specific precipitin arcs. J Immunol. 1960 Jan;84:93–97. [PubMed] [Google Scholar]
  10. REED C. E., BARBEE R. A. PIGEON-BREEDERS' LUNG: A NEWLY OBSERVED INTERSTITIAL PULMONARY DISEASE. JAMA. 1965 Jul 26;193:261–265. doi: 10.1001/jama.1965.03090040005001. [DOI] [PubMed] [Google Scholar]
  11. Tomasi T. B., Jr On the mechanisms of transport and biological significance of antibodies in external secretions. Arthritis Rheum. 1969 Feb;12(1):45–50. doi: 10.1002/art.1780120108. [DOI] [PubMed] [Google Scholar]

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