Skip to main content
Immunology logoLink to Immunology
. 1978 Jul;35(1):125–127.

Antibody induced elimination of the plasmid controlled K88 adhesion factor from a porcine enteropathogen.

M A Linggood, P Porter
PMCID: PMC1457229  PMID: 355123

Abstract

The heat labile K88 antigen which is a product of an episomal gene, was eliminated from a pocrine enteropathogen by passage through media containing sow colostrum antibodies raised against heart stable antigens of E. coli. In consequence the porcine enteropathogen lost its ability to adhere to and aggluinate chicken erythrocytes, and model system for piglet intestinal adhesion and virulence.

Full text

PDF
125

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Mitchell I., Kenworthy R. Attempted elimination of plasmid-determined haemolysin, K88 antigen and enterotoxin from Escherichia coli pathogenic for pigs. J Appl Bacteriol. 1977 Apr;42(2):207–212. doi: 10.1111/j.1365-2672.1977.tb00686.x. [DOI] [PubMed] [Google Scholar]
  2. Porter P., Kenworthy R., Allen W. D. Effect of oral immunisation with E coli antigens on post weaning enteric infection in the young pig. Vet Rec. 1974 Aug 3;95(5):99–104. doi: 10.1136/vr.95.5.99. [DOI] [PubMed] [Google Scholar]
  3. Porter P., Kenworthy R., Holme D. W., Horsfield S. Escherichia coli antigens as dietary additives for oral immunisation of pigs: trials with pig creep feeds. Vet Rec. 1973 Jun 16;92(24):630–636. doi: 10.1136/vr.92.24.630. [DOI] [PubMed] [Google Scholar]
  4. Porter P., Noakes D. E., Allen W. D. Secretory IgA and antibodies to Escherichia coli in porcine colostrum and milk and their significance in the alimentary tract of the young pig. Immunology. 1970 Feb;18(2):245–257. [PMC free article] [PubMed] [Google Scholar]
  5. Rutter J. M., Jones G. W. Protection against enteric disease caused by Escherichia coli--a model for vaccination with a virulence determinant? Nature. 1973 Apr 20;242(5399):531–532. doi: 10.1038/242531a0. [DOI] [PubMed] [Google Scholar]
  6. Salisbury V., Hedges R. W., Datta N. Two modes of "curing" transmissible bacterial plasmids. J Gen Microbiol. 1972 May;70(3):443–452. doi: 10.1099/00221287-70-3-443. [DOI] [PubMed] [Google Scholar]
  7. Sellwood R., Gibbons R. A., Jones G. W., Rutter J. M. Adhesion of enteropathogenic Escherichia coli to pig intestinal brush borders: the existence of two pig phenotypes. J Med Microbiol. 1975 Aug;8(3):405–411. doi: 10.1099/00222615-8-3-405. [DOI] [PubMed] [Google Scholar]
  8. Smith H. W., Linggood M. A. Observations on the pathogenic properties of the K88, Hly and Ent plasmids of Escherichia coli with particular reference to porcine diarrhoea. J Med Microbiol. 1971 Nov;4(4):467–485. doi: 10.1099/00222615-4-4-467. [DOI] [PubMed] [Google Scholar]
  9. Wilson M. R., Hohmann A. W. Immunity to Escherichia coli in pigs: adhesion of enteropathogenic Escherichia coli to isolated intestinal epithelial cells. Infect Immun. 1974 Oct;10(4):776–782. doi: 10.1128/iai.10.4.776-782.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Immunology are provided here courtesy of British Society for Immunology

RESOURCES