Abstract
Hooded Lister rats were sensitized to DNP-ovalbumin. These rats showed a significant alteration in respiratory pattern when challenged with DNP-ovalbumin aerosol. The respiratory response was not produced by challenging sensitized rats with intragastric DNP-ovalbumin. The magnitude of the respiratory response did not correlate with the specific IgE concentration in the serum. A similar pattern of respiratory response was inducible in unsensitized rats by intravenous administration of IgE-rich sera.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Booth B. H., Patterson R., Talbot C. H. Immediate-type hypersensitivity in dogs: cutaneous, anaphylactic, and respiratory responses to ascaris. J Lab Clin Med. 1970 Aug;76(2):181–189. [PubMed] [Google Scholar]
- Church M. K., Collier H. O., James G. W. The inhibition by dexamethasone and disodium cromoglycate of anaphylactic bronchoconstriction in the rat. Br J Pharmacol. 1972 Sep;46(1):56–65. doi: 10.1111/j.1476-5381.1972.tb06848.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Church M. K. Correlation of anaphylactic bronchoconstriction with circulating reaginic antibody level and active cutaneous anaphylaxis in the rat. Immunology. 1975 Sep;29(3):527–534. [PMC free article] [PubMed] [Google Scholar]
- Dobson C., Rockey J. H., Soulsby E. J. Immunoglobulin E antibodies in guinea pigs: characterization of monomeric and polymeric components. J Immunol. 1971 Nov;107(5):1431–1439. [PubMed] [Google Scholar]
- Jarrett E. E., Stewart D. C. Rat IgE production. I. Effect of dose of antigen on primary and secondary reaginic antibody responses. Immunology. 1974 Sep;27(3):365–381. [PMC free article] [PubMed] [Google Scholar]
- Kanyerezi B., Jaton J. C., Bloch K. J. Human and rat gamma E: serologic evidence of homology. J Immunol. 1971 May;106(5):1411–1412. [PubMed] [Google Scholar]
- Patterson R., Talbot C. A comparison of immediate-type respiratory reactions to immunologic and pharmacologic agents in rhesus monkeys. J Allergy Clin Immunol. 1972 May;49(5):292–300. doi: 10.1016/0091-6749(72)90097-8. [DOI] [PubMed] [Google Scholar]
- Stechschulte D. J., Orange R. P., Austen K. F. Immunochemical and biologic properties of rat IgE. I. Immunochemical identification of rat IgE. J Immunol. 1970 Nov;105(5):1082–1086. [PubMed] [Google Scholar]
- Van Hout C. A., Johnson H. G. Synthesis of rat IgE by aerosol immunization. J Immunol. 1972 Mar;108(3):834–836. [PubMed] [Google Scholar]