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. 1980 Dec;41(4):759–787. doi: 10.1007/BF00199524

Antigen-specific T-cell factors.

M J Taussig
PMCID: PMC1458315  PMID: 6161877

Abstract

Antigen-specific T-cell factors are mediator molecules which are produced by helper and suppressor T cells and which can perform the function of those cells in an antigen-specific manner. They probably play an important part in immunoregulation. The major histocompatibility complex has a controlling influence on their structure and activity, while their antigen-recognition properties may be conferred by immunoglobulin V regions. Interest in the factors derives from three related areas of research, namely (i) the problem of T-cell recognition of antigen; (ii) the mechanisms of cellular interactions in antibody production and cell-mediated immunity; and (iii) the genetic control of immune responses. This review discusses the literature up to June 1980 on their production, structure, genetic restriction and mechanism of action.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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