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. 2001 Nov;159(3):1325–1337. doi: 10.1093/genetics/159.3.1325

Mapping quantitative trait Loci using generalized estimating equations.

C Lange 1, J C Whittaker 1
PMCID: PMC1461861  PMID: 11729173

Abstract

A number of statistical methods are now available to map quantitative trait loci (QTL) relative to markers. However, no existing methodology can simultaneously map QTL for multiple nonnormal traits. In this article we rectify this deficiency by developing a QTL-mapping approach based on generalized estimating equations (GEE). Simulation experiments are used to illustrate the application of the GEE-based approach.

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Selected References

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