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. 1961 Oct;154(4):524–552. doi: 10.1097/00000658-196110000-00005

Effects of Acidosis on Cardiovascular Function in Surgical Patients *

George H A Clowes Jr, Gabriel A Sabga, A Konitaxis, R Tomin, Mary Hughes, F A Simeone
PMCID: PMC1465997  PMID: 13880008

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BEECHER H. K., MURPHY A. J. Acidosis during thoracic surgery. J Thorac Surg. 1950 Jan;19(1):50–70. [PubMed] [Google Scholar]
  2. BJORK V. O., HILTY H. J. The arterial oxygen and carbon dioxide tension during the postoperative period in cases of pulmonary resections and thoracoplasties. J Thorac Surg. 1954 May;27(5):455–467. [PubMed] [Google Scholar]
  3. BOYD A. D., TREMBLAY R. E., SPENCER F. C., BAHNSON H. T. Estimation of cardiac output soon after intracardiac surgery with cardiopulmonary bypass. Ann Surg. 1959 Oct;150:613–626. doi: 10.1097/00000658-195910000-00007. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. BRICKNER E. W., DOWDS E. G., WILLITTS B., SELKURT E. E. Mesenteric blood flow as influenced by progressive hypercapnia. Am J Physiol. 1956 Feb;184(2):275–281. doi: 10.1152/ajplegacy.1956.184.2.275. [DOI] [PubMed] [Google Scholar]
  5. CAMPBELL G. S. Cardiac arrest: further studies on the effect of pH changes on vagal inhibition of the heart. Surgery. 1955 Sep;38(3):615–634. [PubMed] [Google Scholar]
  6. CLOWES G. H., Jr, ALICHNIEWICZ A., DEL GUERCIO L. R., GILLESPIE D. The relationship of postoperative acidosis to pulmonary and cardiovascular function. J Thorac Cardiovasc Surg. 1960 Jan;39:1–25. [PubMed] [Google Scholar]
  7. CLOWES G. H., Jr, DEL GUERCIO L. R., BARWINSKY J. The cardiac output in response to surgical trauma. A comparison between patients who survived and those who died. Arch Surg. 1960 Aug;81:212–222. doi: 10.1001/archsurg.1960.01300020040006. [DOI] [PubMed] [Google Scholar]
  8. CLOWES G. H., Jr, DEL GUERCIO L. R. Circulatory response to trauma of surgical operations. Metabolism. 1960 Jan;9:67–81. [PubMed] [Google Scholar]
  9. CLOWES G. H., Jr Extracorporeal maintenance of circulation and respiration. Physiol Rev. 1960 Oct;40:826–919. doi: 10.1152/physrev.1960.40.4.826. [DOI] [PubMed] [Google Scholar]
  10. CLOWES G. H., Jr, HACKEL D. B. Coronary blood flow and myocardial metabolism during hypoxia in adrenalectomized-sympathectomized dogs. Am J Physiol. 1956 Jul;186(1):111–114. doi: 10.1152/ajplegacy.1956.186.1.111. [DOI] [PubMed] [Google Scholar]
  11. CLOWES G. H., Jr, HOPKINS A. L., SIMEONE F. A. A comparison of the physiological effects of hypercapnia and hypoxia in the production of cardiac arrest. Ann Surg. 1955 Sep;142(3):446–459. doi: 10.1097/00000658-195509000-00011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. CLOWES G. H., Jr, KRETCHMER H. E., McBURNEY R. W., SIMEONE F. A. The electro-encephalogram in the evaluation of the effects of anesthetic agents and carbon dioxide accumulation during surgery. Ann Surg. 1953 Oct;138(4):558–569. doi: 10.1097/00000658-195310000-00008. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. ELKINTON J. R., SINGER R. B., BARKER E. S., CLARK J. K. Effects in man of acute experimental respiratory alkalosis and acidosis on ionic transfers in the total body fluids. J Clin Invest. 1955 Nov;34(11):1671–1690. doi: 10.1172/JCI103221. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. ENGEL F. L. The significance of the metabolic changes during shock. Ann N Y Acad Sci. 1952 Sep;55(3):381–393. doi: 10.1111/j.1749-6632.1952.tb26554.x. [DOI] [PubMed] [Google Scholar]
  15. ETSTEN B., LI T. H. Hemodynamic changes during thiopental anesthesia in humans: cardiac output, stroke volume, total peripheral resistance, and intrathoracic blood volume. J Clin Invest. 1955 Mar;34(3):500–510. doi: 10.1172/JCI103099. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. GERBODE F. Some experiences with intracardiac surgery. Surgery. 1959 Jan;45(1):1–7. [PubMed] [Google Scholar]
  17. GIBBON J. H., Jr, ALLBRITTEN F. F., Jr, STAYMAN J. W., Jr, JUDD J. M. A clinical study of respiratory exchange during prolonged operations with an open thorax. Ann Surg. 1950 Oct;132(4):611–625. doi: 10.1097/00000658-195010000-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. GORLIN R., LEWIS B. M. Circulatory adjustments to hypoxia in dogs. J Appl Physiol. 1954 Sep;7(2):180–185. doi: 10.1152/jappl.1954.7.2.180. [DOI] [PubMed] [Google Scholar]
  19. Gremels H., Starling E. H. On the influence of hydrogen ion concentration and of anoxaemia upon the heart volume. J Physiol. 1926 Apr 23;61(2):297–304. doi: 10.1113/jphysiol.1926.sp002294. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. HAMMOND W. G., VANDAM L. D., DAVIS J. M., CARTER R. D., BALL M. R., MOORE F. D. Studies in surgical endocrinology. IV. Anesthetic agents as stimuli to change in corticosteroids and metabolism. Ann Surg. 1958 Aug;148(2):199–211. doi: 10.1097/00000658-195808000-00008. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. HARDY J. D., CARTER T., TURNER M. D. Catechol amine metabolism: peripheral plasma levels of epinephrine (E) and norepinephrine (NE) during laparotomy under different types of anesthesia in dogs, during operation in man (including adrenal vein sampling), and before and following resection of a pheochromocytoma associated with von Recklinghausen's neurofibromatosis. Ann Surg. 1959 Oct;150:666–683. doi: 10.1097/00000658-195910000-00011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. HEILBRUNN A., ALLBRITTEN F. F., Jr Cardiac output during the following surgical operations. Ann Surg. 1960 Aug;152:197–210. doi: 10.1097/00000658-196008000-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. HUCKABEE W. E. Relationships of pyruvate and lactate during anaerobic metabolism. I. Effects of infusion of pyruvate or glucose and of hyperventilation. J Clin Invest. 1958 Feb;37(2):244–254. doi: 10.1172/JCI103603. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Kety S. S., Schmidt C. F. THE EFFECTS OF ALTERED ARTERIAL TENSIONS OF CARBON DIOXIDE AND OXYGEN ON CEREBRAL BLOOD FLOW AND CEREBRAL OXYGEN CONSUMPTION OF NORMAL YOUNG MEN. J Clin Invest. 1948 Jul;27(4):484–492. doi: 10.1172/JCI101995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Lennox W. G., Gibbs E. L. THE BLOOD FLOW IN THE BRAIN AND THE LEG OF MAN, AND THE CHANGES INDUCED BY ALTERATION OF BLOOD GASES. J Clin Invest. 1932 Nov;11(6):1155–1177. doi: 10.1172/JCI100470. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. MAIER H. C., RICH G. W., EICHEN S. Clinical significance of respiratory acidosis during operations. Ann Surg. 1951 Oct;134(4):653–658. doi: 10.1097/00000658-195110000-00012. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. NAHAS G. G., CAVERT H. M. Cardiac depressant effect of CO2 and its reversal. Am J Physiol. 1957 Sep;190(3):483–491. doi: 10.1152/ajplegacy.1957.190.3.483. [DOI] [PubMed] [Google Scholar]
  28. OLMSTED F., ALDRICH F. D. Improved electromagnetic flowmeter; phase detection, a new principle. J Appl Physiol. 1961 Jan;16:197–201. doi: 10.1152/jappl.1961.16.1.197. [DOI] [PubMed] [Google Scholar]
  29. OLSON R. E., SCHWARTZ W. B. Myocardial metabolism in congestive heart failure. Medicine (Baltimore) 1951 Feb;30(1):21–41. doi: 10.1097/00005792-195102000-00002. [DOI] [PubMed] [Google Scholar]
  30. PAGE I. H., OLMSTED F. The influence of respiratory gas mixtures on arterial pressure and vascular reactivity in normal and hypertensive dogs. Circulation. 1951 Jun;3(6):801–819. doi: 10.1161/01.cir.3.6.801. [DOI] [PubMed] [Google Scholar]
  31. PANETH M., SELLERS R., GOTT V. L., WEIRICH W. L., ALLEN P., READ R. C., LILLEHEI C. W. Physiologic studies upon prolonged cardiopulmonary by-pass with the pump-oxygenator with particular reference to (1) acid-base balance, (2) siphon caval drainage. J Thorac Surg. 1957 Nov;34(5):570–579. [PubMed] [Google Scholar]
  32. RICHARDSON D. W., WASSERMAN A. J., PATTERSON J. L., Jr General and regional circulatory responses to change in blood pH and carbon dioxide tension. J Clin Invest. 1961 Jan;40:31–43. doi: 10.1172/JCI104234. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. SANCETTA S. M. The hemodynamic effects of anesthesia. Verh Dtsch Ges Kreislaufforsch. 1957;23:61–79. [PubMed] [Google Scholar]
  34. SECHZER P. H., EGBERT L. D., LINDE H. W., COOPER D. Y., DRIPPS R. D., PRICE H. L. Effect of carbon dioxide inhalation on arterial pressure, ECG and plasma catecholamines and 17-OH corticosteroids in normal man. J Appl Physiol. 1960 May;15:454–458. doi: 10.1152/jappl.1960.15.3.454. [DOI] [PubMed] [Google Scholar]
  35. TAYLOR F. H., ROOS A. Disturbances in acid-base balance during ether anesthesia; with special reference to the changes occurring during thoracic surgery. J Thorac Surg. 1950 Aug;20(2):289–295. [PubMed] [Google Scholar]

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