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. 1962 Feb;155(2):167–174. doi: 10.1097/00000658-196200000-00001

Mechanism of the Gastric Hypersection in the Zollinger-Ellison Syndrome: Successful Extraction of Gastrin-Like Activity from Metastases and Primary Pancreatico-Duodenal Islet Cell Carcinoma *

Stanley R Freisen, Hilda J Tracy, R A Gregory
PMCID: PMC1466056  PMID: 13894989

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DREILING D. A., JANOWITZ H. D. The effect of glucagon on gastric secretion in man. Gastroenterology. 1959 May;36(5):580–581. [PubMed] [Google Scholar]
  2. EISEMAN B., MAYNARD R. M. A noninsulin producing islet cell adenoma associated with progressive peptic ulceration (the Zollinger-Ellison syndrome). Gastroenterology. 1956 Sep;31(3):296–304. [PubMed] [Google Scholar]
  3. FRIESEN S. R., MILLER D. R. Fibrogenic mesodermal tumors, an unusual cause of hyperinsulinism. Am J Surg. 1960 Apr;99:420–423. doi: 10.1016/0002-9610(60)90137-9. [DOI] [PubMed] [Google Scholar]
  4. GOODALE F., Jr, SNIFFEN R. C. Mucosal hypertrophy of the stomach; report of a case. N Engl J Med. 1953 Dec 31;249(27):1105–1107. doi: 10.1056/NEJM195312312492704. [DOI] [PubMed] [Google Scholar]
  5. GREGORY R. A. Gastric secretory responses after portal venous ligation. J Physiol. 1958 Nov 10;144(1):123–137. doi: 10.1113/jphysiol.1958.sp006090. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. GREGORY R. A., TRACY H. J., FRENCH J. M., SIRCUS W. Extraction of a gastrin-like substance from a pancreatic tumour in a case of Zollinger-Ellison syndrome. Lancet. 1960 May 14;1(7133):1045–1048. doi: 10.1016/s0140-6736(60)90932-6. [DOI] [PubMed] [Google Scholar]
  7. MACKENZIE W. C., NORVELL S. T., Jr, MATHEWS B. L., SHNITKA T. K. Islet cell tumours and peptic ulcers; a report of two cases of Zollinger-Ellison syndrome. Can J Surg. 1958 Oct;2(1):6–15. [PubMed] [Google Scholar]
  8. MAYNARD E. P., 3rd, POINT W. W. Steatorrhea associated with ulcerogenic tumor of the pancreas. Am J Med. 1958 Sep;25(3):456–459. doi: 10.1016/0002-9343(58)90085-8. [DOI] [PubMed] [Google Scholar]
  9. OBERHELMAN H. A., Jr, NELSEN T. S., JOHNSON A. N., Jr, DRAGSTEDT L. R., 2nd Ulcerogenic tumors of the duodenum. Ann Surg. 1961 Feb;153:214–227. doi: 10.1097/00000658-196115320-00008. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. OSBORNE M. P., BROWN M. E., LECOMPTE P. M. Ulcerogenic non-beta cell pancreatic islet carcinoma. Studies on the extraction and assay of a possible gastric secretagogue. Am J Surg. 1960 Jul;100:48–53. doi: 10.1016/0002-9610(60)90537-7. [DOI] [PubMed] [Google Scholar]
  11. OSTROW J. D., BLANSHARD G., GRAY S. J. Peptic ulcer in primary hyperparathyroidism. Am J Med. 1960 Nov;29:769–779. doi: 10.1016/0002-9343(60)90111-x. [DOI] [PubMed] [Google Scholar]
  12. POTH E. J., FROMM S. M. The relation of pancreatic secretion to peptic ulcer formation. III. The influence of the hyperglycemic-glycogenolytic factor. Gastroenterology. 1950 Oct;16(2):490–494. [PubMed] [Google Scholar]
  13. RAWSON A. B., ENGLAND M. T., GILLAM G. G., FRENCH J. M., STAMMERS F. A. Zollinger-Ellison syndrome with diarrhoea and malabsorption. Observations on a patient before and after pancreatic islet-cell tumour removal with-out resort. Lancet. 1960 Jul 16;2(7142):131–134. doi: 10.1016/s0140-6736(60)91271-x. [DOI] [PubMed] [Google Scholar]
  14. ROBINSON R. M., HARRIS K., HLAD C. J., EISEMAN B. Effect of glucagon on gastric secretion. Proc Soc Exp Biol Med. 1957 Nov;96(2):518–520. doi: 10.3181/00379727-96-23525. [DOI] [PubMed] [Google Scholar]
  15. RUDOLF L. E., DAMMIN G. F., MOORE F. D. Intractable peptic ulcer and endocrine adenomas with pituitary amphophilic hyperplasia. A reinterpretation of the Ellison-Zollinger syndrome. Surgery. 1960 Jul;48:170–184. [PubMed] [Google Scholar]
  16. SUMMERSKILL W. H. Malabsorption and jejunal ulceration due to gastric hypersecretion with pancreatic islet-cell hyperplasia. Lancet. 1959 Jan 17;1(7064):120–123. doi: 10.1016/s0140-6736(59)90003-0. [DOI] [PubMed] [Google Scholar]
  17. ZOLLINGER R. M., CRAIG T. V. Endocrine tumors and peptic ulcer. Am J Med. 1960 Nov;29:761–768. doi: 10.1016/0002-9343(60)90110-8. [DOI] [PubMed] [Google Scholar]
  18. ZOLLINGER R. M., CRAIG T. V. Ulcerogenic tumors of the pancreas. Am J Surg. 1960 Apr;99:424–432. doi: 10.1016/0002-9610(60)90138-0. [DOI] [PubMed] [Google Scholar]
  19. ZOLLINGER R. M., ELLISON E. H. Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas. Ann Surg. 1955 Oct;142(4):709-23; discussion, 724-8. [PMC free article] [PubMed] [Google Scholar]
  20. ZUBROD C. G., WERMER P., PIEPER W., HILBISH T. F., SMITH R., DUTCHER T. Acromegaly, jejunal ulcers and hypersecretion of gastric juice: clinical-pathological conference at the National Institutes of Health. Ann Intern Med. 1958 Dec;49(6):1389–1409. doi: 10.7326/0003-4819-49-6-1389. [DOI] [PubMed] [Google Scholar]

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