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. 1986 Apr;66:73–80. doi: 10.1289/ehp.866673

Acute symptoms following exposure to grain dust in farming.

J Manfreda, V Holford-Strevens, M Cheang, C P Warren
PMCID: PMC1474397  PMID: 3709486

Abstract

History of acute symptoms (cough, wheezing, shortness of breath, fever, stuffy nose, and skin itching/rash) following exposure to grain dust was obtained from 661 male and 535 female current and former farmers. These symptoms were relatively common: 60% of male and 25% of female farmers reported at least one such symptom on exposure to grain dust. Association of cough, wheezing, shortness of breath, and stuffy nose with skin reactivity and capacity to form IgE is consistent with an allergic nature of these symptoms. Barley and oats dust were perceived as dust most often producing symptoms. On the other hand, grain fever showed a different pattern, i.e., it was not associated with either skin reactivity or total IgE. Smoking might modify the susceptibility to react to grain dust with symptoms. Only those who reported wheezing on exposure to grain dust may have an increased risk to develop chronic airflow obstruction.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Broder I., Mintz S., Hutcheon M., Corey P., Silverman F., Davies G., Leznoff A., Peress L., Thomas P. Comparison of respiratory variables in grain elevator workers and civic outside workers of Thunder Bay, Canada. Am Rev Respir Dis. 1979 Feb;119(2):193–203. doi: 10.1164/arrd.1979.119.2.193. [DOI] [PubMed] [Google Scholar]
  2. COHEN V. L., OSGOOD H. Disability due to inhalation of grain dust. J Allergy. 1953 May;24(3):193–211. doi: 10.1016/0021-8707(53)90001-x. [DOI] [PubMed] [Google Scholar]
  3. Chan-Yeung M., Schulzer M., MacLean L., Dorken E., Grzybowski S. Epidemiologic health survey of grain elevator workers in British Columbia. Am Rev Respir Dis. 1980 Feb;121(2):329–338. doi: 10.1164/arrd.1980.121.2.329. [DOI] [PubMed] [Google Scholar]
  4. Chan-Yeung M., Wong R., MacLean L. Respiratory abnormalities among grain elevator workers. Chest. 1979 Apr;75(4):461–467. doi: 10.1378/chest.75.4.461. [DOI] [PubMed] [Google Scholar]
  5. Cockcroft A. E., McDermott M., Edwards J. H., McCarthy P. Grain exposure--symptoms and lung function. Eur J Respir Dis. 1983 Apr;64(3):189–196. [PubMed] [Google Scholar]
  6. Darke C. S., Knowelden J., Lacey J., Milford Ward A. Respiratory disease of workers harvesting grain. Thorax. 1976 Jun;31(3):294–302. doi: 10.1136/thx.31.3.294. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Davies R. J., Green M., Schofield N. M. Recurrent nocturnal asthma after exposure to grain dust. Am Rev Respir Dis. 1976 Nov;114(5):1011–1019. doi: 10.1164/arrd.1976.114.5.1011. [DOI] [PubMed] [Google Scholar]
  8. DoPico G. A., Reddan W., Flaherty D., Tsiatis A., Peters M. E., Rao P., Rankin J. Respiratory abnormalities among grain handlers: a clinical, physiologic, and immunologic study. Am Rev Respir Dis. 1977 Jun;115(6):915–927. doi: 10.1164/arrd.1977.115.6.915. [DOI] [PubMed] [Google Scholar]
  9. Farant J. P., Moore C. F. Dust exposures in the Canadian grain industry. Am Ind Hyg Assoc J. 1978 Mar;39(3):177–194. doi: 10.1080/0002889778507741. [DOI] [PubMed] [Google Scholar]
  10. Hendrick D. J., Davies R. J., Pepys J. Bakers' asthma. Clin Allergy. 1976 May;6(3):241–250. doi: 10.1111/j.1365-2222.1976.tb01903.x. [DOI] [PubMed] [Google Scholar]
  11. Holford-Strevens V., Warren P., Wong C., Manfreda J. Serum total immunoglobulin E levels in Canadian adults. J Allergy Clin Immunol. 1984 Apr;73(4):516–522. doi: 10.1016/0091-6749(84)90363-4. [DOI] [PubMed] [Google Scholar]
  12. Ingram C. G., Jeffrey I. G., Symington I. S., Cuthbert O. D. Bronchial provocation studies in farmers allergic to storage mites. Lancet. 1979 Dec 22;2(8156-8157):1330–1332. doi: 10.1016/s0140-6736(79)92814-9. [DOI] [PubMed] [Google Scholar]
  13. Klaustermeyer W. B., Bardana E. J., Jr, Hale F. C. Pulmonary hypersensitivity to Alternaria and Aspergillus in baker's asthma. Clin Allergy. 1977 May;7(3):227–233. doi: 10.1111/j.1365-2222.1977.tb01447.x. [DOI] [PubMed] [Google Scholar]
  14. Kleinfeld M., Messite J., Swencicki R. E., Shapiro J. A clinical and physiologic study of grain handlers. Arch Environ Health. 1968 Mar;16(3):380–384. doi: 10.1080/00039896.1968.10665074. [DOI] [PubMed] [Google Scholar]
  15. Lunn J. A. Millworkers' asthma: allergic responses to the grain weevil (Sitophilus granarius). Br J Ind Med. 1966 Apr;23(2):149–152. doi: 10.1136/oem.23.2.149. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Mavrina E. A. O spetsificheskoi diagnostike "zernovoi (gribkovoi) likhoradki" i khronicheskogo mikticheskogo bronkhita u lits, rabotaiushchikh s zernom. Gig Tr Prof Zabol. 1966 Dec;10(12):11–15. [PubMed] [Google Scholar]
  17. SKOULAS A., WILLIAMS N., MERRIMAN J. E. EXPOSURE TO GRAIN DUST. II. A CLINICAL STUDY OF THE EFFECTS. J Occup Med. 1964 Sep;6:359–372. [PubMed] [Google Scholar]
  18. Tse K. S., Warren P., Janusz M., McCarthy D. S., Cherniack R. M. Respiratory abnormalities in workers exposed to grain dust. Arch Environ Health. 1973 Aug;27(2):74–77. doi: 10.1080/00039896.1973.10666321. [DOI] [PubMed] [Google Scholar]
  19. WILLIAMS N., SKOULAS A., MERRIMAN J. E. EXPOSURE TO GRAIN DUST. I. A SURVEY OF THE EFFECTS. J Occup Med. 1964 Aug;6:319–329. [PubMed] [Google Scholar]
  20. Warren C. P., Holford-Strevens V., Sinha R. N. Sensitization in a grain handler to the storage mite Lepidoglyphus destructor (Schrank). Ann Allergy. 1983 Jan;50(1):30–33. [PubMed] [Google Scholar]
  21. Warren C. P., Holford-Strevens V., Wong C., Manfreda J. The relationship between smoking and total immunoglobulin E levels. J Allergy Clin Immunol. 1982 Apr;69(4):370–375. doi: 10.1016/0091-6749(82)90148-8. [DOI] [PubMed] [Google Scholar]
  22. Warren C. P., Manfreda J. Respiratory symptoms in Manitoba farmers: association with grain and hay handling. Can Med Assoc J. 1980 Jun 7;122(11):1259–1264. [PMC free article] [PubMed] [Google Scholar]
  23. Warren P., Cherniack R. M., Tse K. S. Hypersensitivity reactions to grain dust. J Allergy Clin Immunol. 1974 Mar;53(3):139–149. doi: 10.1016/0091-6749(74)90002-5. [DOI] [PubMed] [Google Scholar]
  24. Weber A. C., Scharfetter C. The syndrome concept: history and statistical operationalizations. Psychol Med. 1984 May;14(2):315–325. doi: 10.1017/s0033291700003585. [DOI] [PubMed] [Google Scholar]
  25. doPico G. A., Jacobs S., Flaherty D., Rankin J. Pulmonary reaction to durum wheat; a constituent of grain dust. Chest. 1982 Jan;81(1):55–61. doi: 10.1378/chest.81.1.55. [DOI] [PubMed] [Google Scholar]

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