Abstract
Mass testing of dogs in Canada for the presence of Dirofilaria immitis has been ongoing since 1977. Since that time, there have also been changes in the diagnostic tests available to detect the presence of heartworm and changes in the therapy for heartworm, which necessitate a reevaluation of heartworm screening as currently practiced in Canada. The principles of evidence-based medicine were used to determine the prevalence of heartworm infection in various dog populations, and the effectiveness of screening these populations. The annual surveys of heartworm testing have shown that Canada is a low prevalence area (0.16%), with most of the test-positive dogs located in southern Ontario (0.19%), southern Manitoba (0.18%), southern Quebec (0.09%), and the southern Okanagan Valley (0.04%). Foci of higher prevalence are found within these 4 main geographic areas. Furthermore, the prevalence of heartworm infection is higher in the population of dogs not on preventative medication (0.62%), when compared to the population of dogs on preventative medication (0.04%). The evidence indicates that a heartworm diagnostic test applied to an asymptomatic dog on preventative medication contributes little information regarding the heartworm infection status of that dog. However, testing of a dog characterized as being high risk will provide clinically useful information. Recommendations regarding the testing of dogs for heartworm in Canada are derived on the basis of available evidence.
Full text
PDFImages in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Atwell R. B., Sheridan A. B., Baldock F. C. An evaluation of the Dirochek test for detection of Dirofilaria immitis antigen in dogs. Aust Vet J. 1988 May;65(5):161–162. doi: 10.1111/j.1751-0813.1988.tb14451.x. [DOI] [PubMed] [Google Scholar]
- Blair L. S., Campbell W. C. Efficacy of Ivermectin against Dirofilaria immitis larvae in dogs 31, 60, and 90 days after injection. Am J Vet Res. 1980 Dec;41(12):2108–2108. [PubMed] [Google Scholar]
- Grieve R. B., Frank G. R., Stewart V. A., Parsons J. C., Belasco D. L., Hepler D. I. Chemoprophylactic effects of milbemycin oxime against larvae of Dirofilaria immitis during prepatent development. Am J Vet Res. 1991 Dec;52(12):2040–2042. [PubMed] [Google Scholar]
- Kitagawa H., Sasaki Y., Kumasaka J., Mikami C., Kitoh K., Kusano K. Clinical and laboratory changes after administration of milbemycin oxime in heartworm-free and heartworm-infected dogs. Am J Vet Res. 1993 Apr;54(4):520–526. [PubMed] [Google Scholar]
- Knight D. H. Heartworm infection. Vet Clin North Am Small Anim Pract. 1987 Nov;17(6):1463–1518. doi: 10.1016/s0195-5616(87)50012-2. [DOI] [PubMed] [Google Scholar]
- Knight D. H., Lok J. B. Seasonality of heartworm infection and implications for chemoprophylaxis. Clin Tech Small Anim Pract. 1998 May;13(2):77–82. doi: 10.1016/S1096-2867(98)80010-8. [DOI] [PubMed] [Google Scholar]
- Mackenzie G. W., Waldie J. M. British Columbia. Heartworms in dogs in British Columbia. Can Vet J. 1991 Aug;32(8):501–501. [PMC free article] [PubMed] [Google Scholar]
- Martini M., Capelli G., Poglayen G., Bertotti F., Turilli C. The validity of some haematological and ELISA methods for the diagnosis of canine heartworm disease. Vet Res Commun. 1996;20(4):331–339. doi: 10.1007/BF00366539. [DOI] [PubMed] [Google Scholar]
- Matherne C. M., Green S. P., Corwin R. M., Kelley S. T. Detection of circulating Dirofilaria immitis antigens in random source laboratory dogs: evaluation of two commercial serodiagnostic tests. Lab Anim Sci. 1988 Oct;38(5):584–587. [PubMed] [Google Scholar]
- Owen J., Slocombe D., McMillan I. Heartworm in dogs in Canada in 1985. Can Vet J. 1986 Sep;27(9):324–328. [PMC free article] [PubMed] [Google Scholar]
- Owen J., Slocombe D., McMillan I. Heartworm in dogs in Canada in 1986. Can Vet J. 1987 Aug;28(8):491–495. [PMC free article] [PubMed] [Google Scholar]
- Slocombe J. O. Heartworm in dogs in Canada in 1977. Can Vet J. 1978 Sep;19(9):244–247. [PMC free article] [PubMed] [Google Scholar]
- Slocombe J. O. Heartworm in dogs in Canada in 1989. Can Vet J. 1990 Jul;31(7):499–505. [PMC free article] [PubMed] [Google Scholar]
- Slocombe J. O., McMillan I. Heartworm in dogs in Canada in 1978. Can Vet J. 1979 Oct;20(10):284–287. [PMC free article] [PubMed] [Google Scholar]
- Slocombe J. O., McMillan I. Heartworm in dogs in Canada in 1979. Can Vet J. 1980 May;21(5):159–161. [PMC free article] [PubMed] [Google Scholar]
- Slocombe J. O., McMillan I. Heartworm in dogs in Canada in 1980. Can Vet J. 1981 Jun;22(6):201–203. [PMC free article] [PubMed] [Google Scholar]
- Slocombe J. O., McMillan I. Heartworm in dogs in Canada in 1981. Can Vet J. 1982 Jul;23(7):219–221. [PMC free article] [PubMed] [Google Scholar]
- Slocombe J. O., McMillan I. Heartworm in dogs in Canada in 1982. Can Vet J. 1983 Jul;24(7):227–229. [PMC free article] [PubMed] [Google Scholar]
- Slocombe J. O., McMillan I. Heartworm in dogs in Canada in 1983. Can Vet J. 1984 Sep;25(9):347–350. [PMC free article] [PubMed] [Google Scholar]
- Slocombe J. O., McMillan I. Heartworm in dogs in Canada in 1984. Can Vet J. 1985 Oct;26(10):323–327. [PMC free article] [PubMed] [Google Scholar]
- Slocombe J. O., McMillan I. Heartworm in dogs in Canada in 1987. Can Vet J. 1988 Aug;29(8):641–646. [PMC free article] [PubMed] [Google Scholar]
- Slocombe J. O., McMillan I. Heartworm in dogs in Canada in 1988. Can Vet J. 1989 Jun;30(6):504–508. [PMC free article] [PubMed] [Google Scholar]
- Slocombe J. O., Villeneuve A. Heartworm in dogs in Canada in 1991. Can Vet J. 1993 Oct;34(10):630–633. [PMC free article] [PubMed] [Google Scholar]