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. 1989 Jan;209(1):51–56. doi: 10.1097/00000658-198901000-00008

Effect of a prior portasystemic shunt on subsequent liver transplantation.

J J Brems 1, J R Hiatt 1, A S Klein 1, J M Millis 1, J O Colonna 1, W J Quinones-Baldrich 1, K P Ramming 1, R W Busuttil 1
PMCID: PMC1493874  PMID: 2642690

Abstract

Fifteen patients who had a prior portasystemic shunt underwent orthotopic liver transplantation. Shunt types were portacaval in six patients, H-graft mesocaval in six, distal splenorenal in two, and proximal splenorenal in one. Mean blood loss and hospital stay were highest in the portacaval group. Retransplants (two patients) and deaths (two patients) also were limited to this group. In this report, technical considerations, advantages, and disadvantages of the various shunt types are described. Management of patients with late stages of portal hypertension must include estimation of the effects of a portasystemic shunt on subsequent liver transplantation. It is concluded that portacaval shunts should be avoided in patients who may be considered for transplantation. Distal splenorenal shunts are best performed in younger patients with intractable variceal bleeding who are not expected to require transplantation in the near future. A mesocaval H-graft is the shunt of choice in patients who are current liver transplant candidates.

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Selected References

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  1. Brems J. J., Hiatt J. R., Colonna J. O., 2nd, el-Khoury G., Quiñones W. J., Ramming K. P., Ziomek S., Busuttil R. W. Variables influencing the outcome following orthotopic liver transplantation. Arch Surg. 1987 Oct;122(10):1109–1111. doi: 10.1001/archsurg.1987.01400220019001. [DOI] [PubMed] [Google Scholar]
  2. Busuttil R. W., Colonna J. O., 2nd, Hiatt J. R., Brems J. J., el Khoury G., Goldstein L. I., Quinones-Baldrich W. J., Abdul-Rasool I. H., Ramming K. P. The first 100 liver transplants at UCLA. Ann Surg. 1987 Oct;206(4):387–402. doi: 10.1097/00000658-198710000-00001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Busuttil R. W. Selective and nonselective shunts for variceal bleeding. A prospective study of 103 patients. Am J Surg. 1984 Jul;148(1):27–35. doi: 10.1016/0002-9610(84)90285-x. [DOI] [PubMed] [Google Scholar]
  4. Esquivel C. O., Klintmalm G., Iwatsuki S., Makowka L., Gordon R. D., Tzakis A., Starzl T. E. Liver transplantation in patients with patent splenorenal shunts. Surgery. 1987 Apr;101(4):430–432. [PMC free article] [PubMed] [Google Scholar]
  5. Langer B., Rotstein L. E., Stone R. M., Taylor B. R., Patel S. C., Blendis L. M., Colapinto R. F. A prospective randomized trial of the selective distal splenorenal shunt. Surg Gynecol Obstet. 1980 Jan;150(1):45–48. [PubMed] [Google Scholar]
  6. Lerut J., Tzakis A. G., Bron K., Gordon R. D., Iwatsuki S., Esquivel C. O., Makowka L., Todo S., Starzl T. E. Complications of venous reconstruction in human orthotopic liver transplantation. Ann Surg. 1987 Apr;205(4):404–414. doi: 10.1097/00000658-198704000-00011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Maillard J. N., Flamant Y. M., Hay J. M., Chandler J. G. Selectivity of the distal splenorenal shunt. Surgery. 1979 Nov;86(5):663–671. [PubMed] [Google Scholar]
  8. Smith R. B., 3rd, Warren W. D., Salam A. A., Millikan W. J., Ansley J. D., Galambos J. T., Kutner M., Bain R. P. Dacron interposition shunts for portal hypertension. An analysis of morbidity correlates. Ann Surg. 1980 Jul;192(1):9–17. doi: 10.1097/00000658-198007000-00002. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Warren W. D., Zeppa R., Fomon J. J. Selective trans-splenic decompression of gastroesophageal varices by distal splenorenal shunt. Ann Surg. 1967 Sep;166(3):437–455. doi: 10.1097/00000658-196709000-00011. [DOI] [PMC free article] [PubMed] [Google Scholar]

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