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. 1982 Jun 12;284(6331):1738–1740. doi: 10.1136/bmj.284.6331.1738

Predictive value of SS-B precipitating antibodies in Sjoögren's syndrome.

D A Isenberg, L Hammond, C Fisher, M Griffiths, J Stewart, G F Bottazzo
PMCID: PMC1498670  PMID: 6805691

Abstract

As part of a screening programme several patients were identified with antibodies to the nuclear antigen SS-B. Fifteen were examined and 11 found to have Sjögren's syndrome, though this had not been suspected by most of the referring physicians. In contrast, among a group of 17 patients with overt Sjögren's syndrome, most of whom also had rheumatoid arthritis, only one had antibodies to SS-B. Patients presenting with polyarthralgia found to be SS-B positive may be likely to develop Sjögren's syndrome but unlikely to develop rheumatoid arthritis. The detection of SS-B antibodies may antedate clinical evidence of Sjögren's syndrome by months or even years. These results emphasise the clinical heterogeneity of Sjögren's syndrome.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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